AI Article Synopsis
- Gallic acid has antimicrobial properties, but its effectiveness can be enhanced through photoirradiation which generates reactive oxygen species.
- When Staphylococcus aureus was treated with both gallic acid and blue LED light, it resulted in a significant reduction of viable bacteria within 15 minutes.
- The study concludes that the formation of hydroxyl radicals during this photo-oxidation process is crucial for boosting the antimicrobial action of gallic acid.
Article Abstract
It is known that gallic acid shows antimicrobial activity. In the present study, photoirradiation induced reactive oxygen species formation was investigated for augmentation of the antimicrobial activity of gallic acid. Staphylococcus aureus suspended in 4 mmol/L gallic acid was exposed to blue light of a LED at 400 nm. This treatment killed the bacteria, and a >5-log reduction of the viable counts was observed within 15 min. By contrast, neither the LED treatment alone nor the treatment with gallic acid alone showed substantial bactericidal effect. When hydroxyl radical scavengers were added to the suspension, the bactericidal effect of photoirradiated gallic acid was attenuated. Furthermore, electron spin resonance analysis demonstrated that hydroxyl radicals were generated by the photoirradiation of gallic acid. Thus, the present study suggests that the photo-oxidation can enhance the antimicrobial activity of gallic acid via hydroxyl radical formation.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/jf303177p | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Seasonal Phenolic Profile, Antioxidant and Photoprotective Activities of Psidium guajava Leaves.
Chem Biodivers
December 2024
Regional University of Blumenau: Universidade Regional de Blumenau, Natural Sciences, Antônio da Veiga, 140, 89012-900, Blumenau, BRAZIL.
This study evaluated the phytochemicals from extracts of Psidium guajava L. leaves (PGE), and its antioxidant and photoprotective effects. PGE showed constant production of total phenolics and maintained high antioxidant capacity across seasons and years.
View Article and Find Full Text PDFNutritional, Antioxidant, and Functional Properties of Cameroonian Cowpea and Bambara Groundnut and Their Culinary Forms.
Cureus
November 2024
Department of Biochemistry, University of Dschang, Dschang, CMR.
Background Voandzou and cowpea are two legumes commonly used in African dishes as alternative sources of proteins. The present study aimed to evaluate the effects of steaming and frying on the nutritional and functional properties of Cameroonian cowpea () and Bambara groundnut (). Methodology The nutritional values, as well as the antioxidant, alpha-amylase, and alpha-glucosidase inhibitory activities of "koki" and "beignet koki," which are the traditional steamed dish and fritters made from cowpea and Bambara groundnut, respectively, were assessed.
View Article and Find Full Text PDFA hybrid artificial neural network and multi-objective genetic algorithm approach to optimize extraction conditions of Mentha longifolia and biological activities.
Sci Rep
December 2024
Department of Pharmacy Services, Vocational School of Health Services, Osmaniye Korkut Ata University, Osmaniye, Turkey.
In this work, artificial neural network coupled with multi-objective genetic algorithm (ANN-NSGA-II) has been used to develop a model and optimize the conditions for the extracting of the Mentha longifolia (L.) L. plant.
View Article and Find Full Text PDFThe comparison of the antioxidant, antibacterial and antiviral potential of Polish fir honeydew and Manuka honeys.
Sci Rep
December 2024
Department of Chemistry and Food Toxicology, Institute of Food Technology and Nutrition, University of Rzeszow, Ćwiklińskiej 1a St, Rzeszow, 35-601, Poland.
The aim of the present study was to compare the antioxidant, antibacterial and antiviral activities of Podkarpackie coniferous honeydew honey and Manuka honey. The quality of tested honey samples (honeydew-12 and Manuka-4) regarding honey standard was evaluated as well as additional indicators (methylglyoxal, total phenolics and HPTLC phenolic profile, antioxidant potential, glucose oxidase activity, and hydrogen peroxide) were compared. Antibacterial potential was analyzed against Gram-positive (S.
View Article and Find Full Text PDFAntihyperglycemic activity and bioguided isolation of phenolic compounds with antioxidant and cytotoxic properties from Syzygium malaccense leaves.
Fitoterapia
December 2024
Department of Chemistry, Universidade Tecnológica Federal do Paraná (UTFPR), Pato Branco, PR 85503-390, Brazil.
This study investigated the antihyperglycemic potential of a hydroalcoholic extract from Syzygium malaccense leaves (E-SM) and isolate phenolic compounds with antioxidant and cytotoxic activities through a bioguided assay. The aim was to explore the therapeutic properties of S. malaccense in managing hyperglycemia and oxidative stress-related conditions.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!