This analysis of changes in the immune status of patients operated for splenic lesions is based on the observations of 126 subjects. Fifty of them underwent autolientransplantation and 26 conservative surgery. The main parameters of humoral and cellular immunity were measured along with changes in the microflora. Splenectomy was shown to cause changes in the characteristics of both cellular and humoral immunity. Autolientransplantation caused a significant decrease in the serum level of total complement and its C3- and C-4 fractions while the amount of circulating immune complexes increased All other parameters of the immune status remained unaltered The best outcome of the treatment was documented after conservative surgery.
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