Objectives: This study aims to compare the carotid artery doses applied with various radiotherapy techniques for the treatment of T1N0 glottic larynx cancer.
Patients And Methods: Five patients were simulated with using computed tomography (CT). Clinical (CTV) and planning target volumes (PTV) were created for T1N0 glottic larynx cancer. Planning risk volumes (PRV) were constructed for carotid arteries and spinal cord. Three irradiation planning, opposed lateral box field (OLBF), three dimension conformal radiation therapy (3DCRT), intensity modulated radiation therapy (IMRT) were done for each patient. Over 95% of planned target volumes were loaded with predetermined dose (a total of 62.25 Gy of 2.25 Gy daily dose).
Results: The comparison of the treatment planning of five T1 glottic larynx cancer, three involving the right vocal cord and two involving the left vocal cord, the technique of IMRT planning was provided the best carotid-sparing doses. Mean carotid V35, V50, and V63 values including OLBF, 3DCRT, and IMRT were 70%, 47%, 35%; 55%, 15%, 5% and 28%, 6%, 0%, respectively. The statistical comparison of V35, V50 and V63 revealed significant values for OLBF and IMRT. Dose of spinal cord did not exceed 45 Gy for any of radiation treatment planning. Between the three techniques, there was no significant difference in terms of conformity index and dose distribution was homogenous with all techniques.
Conclusion: It is obvious that IMRT planning technique can decrease the carotid artery radiation doses in early stage glottic larynx cancer.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.5606/kbbihtisas.2012.052 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The Modulation of Fibrosis in Vocal Fold Repair: A Study on c-Met Agonistic Antibodies and Hepatocyte Growth in Animal Studies.
Medicina (Kaunas)
December 2024
Department of Otolaryngology-Head and Neck Surgery, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea.
: Damage to the vocal folds frequently results in fibrosis, which can degrade vocal quality due to the buildup of collagen and modifications in the extracellular matrix (ECM). Conventional treatments have shown limited success in reversing fibrotic changes. Hepatocyte growth factor (HGF) and c-Met-targeting antibodies are promising due to their potential to inhibit fibrosis and promote regeneration.
View Article and Find Full Text PDFComparison of neutral and sniffing position for ease of endotracheal intubation using Airtraq optical laryngoscope-A randomized trial.
J Anaesthesiol Clin Pharmacol
August 2024
Department of Anesthesia and Critical Care, Pt. B. D. Sharma PGIMS, Rohtak, Haryana, India.
Background: Traditionally, the sniffing position has been considered a standard head and neck position during direct laryngoscopy. The perfect head and neck position for video laryngoscopy has yet not been described. Hence, we planned the present study to compare the neutral and sniffing position for ease of intubation using Airtraq.
View Article and Find Full Text PDFRadiographic Predictors of Difficult Fiberscopic Intubation During General Anesthesia in Patients With a Cervical Collar to Simulate a Difficult Airway.
J Neurosurg Anesthesiol
January 2025
Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.
Background: Predictors of difficult fiberscopic intubation have not been fully elucidated. This study focused on identifying radiographic predictors of difficult fiberscopic intubation during general anesthesia in patients with a cervical collar.
Methods: This retrospective study included unconscious patients who underwent orotracheal intubation using a flexible fiberscope while wearing a cervical collar to simulate a difficult airway.
New Findings in Developmental Studies of Laryngeal Mound With a Reference to Its Attached Structures in Japanese Quail (Coturnix coturnix Japonica).
Microsc Res Tech
January 2025
Department of Anatomy and Embryology, Faculty of Veterinary Medicine, Assiut University, Assiut, Egypt.
The laryngeal mound (LM) formed the caudal part of the pharyngeal floor, which varied in position, shape, and length at different ages. This work aimed to study the morphogenesis of the LM in the embryonic and post hatching periods grossly, histologically, and by scanning electron microscopy using forty-eight Japanese quails. The LM primordia appeared on the 8th day of incubation as a raised elevation carried on a deep median symmetrical sulcus (glottis primordium).
View Article and Find Full Text PDFHow does head position affect laryngeal vision with a video laryngeal mask airway?
Front Med (Lausanne)
December 2024
Department of Anaesthesiology and Intensive Therapy, Medical University of Lodz, Łódź, Poland.
Background: The Laryngeal Mask Airway Vision Mask (LMA VM) is a supraglottic airway device (SAD) with a vision guidance system. The ideal head and neck position for direct laryngoscopy is known, but the ideal position for placing a LMA is not. The objective of this study is to evaluate and compare the optimal position for placement of a video laryngeal mask airway.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!