Does local context (e.g., city of residence) matter for self and well-being? We theorized that it does because local contexts diverge in prevalent historically-derived ideas, norms, and products. Through historical analysis, studies of norms (tightness-looseness; Study 1) and cultural products (content analyses of newspaper headlines, venture capital firm websites, hospital websites; Studies 2-4), and studies assessing individuals' self and well-being (Studies 5-7), we compared Boston and San Francisco-similar cities on many metrics. We find that self and well-being are, in some important part, local. Reflecting themes of "old and established," Boston's history and cultural products emphasize tradition, status, and community, and social norms are relatively tight; accordingly feelings and selves are socially contingent. In contrast, reflecting themes of "new and free," San Francisco's history and cultural products emphasize unlimited possibility, egalitarianism, and innovation, and social norms are relatively loose; accordingly feelings and selves are relatively less contingent on others.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1177/0146167212458125 | DOI Listing |
Curr Gene Ther
January 2025
Research Group Medical Biotechnology & Bioengineering, TH Köln - University of Applied Sciences, Leverkusen, Germany.
Gamma-Retroviral (RVVs) and lentiviral vectors (LVVs) represent indispensable tools in somatic gene therapy, mediating the efficient, stable transfer of therapeutic genes into a variety of human target cells. LVVs, in contrast to RVVs, are capable of stably genetically modifying non-proliferating target cells, making them the superior instrument in cell and gene therapy. To date, the LVV manufacturing process employs human embryonic kidney cells (HEK293) and derivatives thereof transiently transfected with multiple plasmids encoding the required viral vector components.
View Article and Find Full Text PDFSynth Syst Biotechnol
June 2025
Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, Jiangsu 214122, China.
Riboflavin, an important vitamin utilized in pharmaceutical products and as a feed additive, is mainly produced by metabolically engineered bacterial fermentation. However, the reliance on antibiotics in the production process leads to increased costs and safety risks. To address these challenges, an antibiotic-free riboflavin producer was constructed using metabolic engineering approaches coupled with a novel plasmid stabilization system.
View Article and Find Full Text PDFFront Trop Dis
December 2024
Parasite and Vector Research Unit (PAVRU), Department of Microbiology and Parasitology, University of Buea, Buea, Cameroon.
Background: is transmitted by species and affects hundred millions of inhabitants in about 33 countries in sub-Saharan Africa. It is known that Mansonellosis due to do not result in a clear clinical picture, but down-regulates the immunity of patients predisposing them to other diseases like tuberculosis, HIV and malaria or damping vaccine efficacy. However, research about novel drugs against this filarial nematode is missing because of the lack of parasite material.
View Article and Find Full Text PDFHeliyon
January 2025
Laboratory of Social and Solidarity Economy Governance and Development (LARESSGD), Department of Economics, Faculty of Law Economics and Social Sciences, Cadi Ayyad University, Marrakech, Morocco.
Early school dropout rates in Morocco exhibit widespread spatial imbalances leading to adverse consequences. Indeed, there is thus a pressing need to investigate the factors contributing to the phenomenon. To this end, this study conducts a multivariate spatial analysis of 75 provinces in Morocco.
View Article and Find Full Text PDFHeliyon
January 2025
Functional Omics and Bioprocess Development Laboratory, Institute of Biological Sciences, Faculty of Science, Universiti Malaya, Kuala Lumpur, 50603, Malaysia.
Eutrophication and hypereutrophication in lakes foster harmful blue-green algal blooms, which pose a significant threat to the ecological health of freshwater reservoirs. This study investigated the effectiveness of the bio-flocculation approach using the fungus strain BGF4A1 to remove these harmful blooms, specifically targeting cyanobacterial species like PCC-7914. Key flocculation parameters, cyanobacterial concentrations, adsorption kinetics, and pellet morphology were explored in this research.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!