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Residue-residue contacts: application to analysis of secondary structure interactions. | LitMetric

Residue-residue contacts: application to analysis of secondary structure interactions.

Methods Mol Biol

Department of Biology, MIT, Cambridge, MA, USA.

Published: January 2013

Protein structures and their complexes are formed and stabilized by interactions, both inside and outside of the protein. Analysis of such interactions helps in understanding different levels of structures (secondary, super-secondary, and oligomeric states). It can also assist molecular biologists in understanding structural consequences of modifying proteins and/or ligands. In this chapter, our definition of atom-atom and residue-residue contacts is described and applied to analysis of protein-protein interactions in dimeric β-sandwich proteins.

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http://dx.doi.org/10.1007/978-1-62703-065-6_10DOI Listing

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