Deciphering DNA-based asymmetric catalysis through intramolecular Friedel-Crafts alkylations.

Chem Commun (Camb)

Department of Chemistry, Graduate School of Science, Kyoto University, Kitashirakawa-oiwakecho, Sakyo-ku, Kyoto 606-8502, Japan.

Published: October 2012

We describe asymmetric intramolecular Friedel-Crafts alkylations with a DNA-based hybrid catalyst and propose a plausible binding model. This study shows promise for studying relationships between the helical chirality of DNA and enantioselectivity of the chemical reaction.

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Source
http://dx.doi.org/10.1039/c2cc35625bDOI Listing

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