[Thrombotic microangiopathy with anti-ADAMTS 13 antibodies revealing an acute Q fever].

Rev Med Interne

Clinique de médecine interne, hôpital Michallon, CHU de Grenoble, BP 217, 38043 Grenoble cedex 09, France.

Published: November 2012

Introduction: Q fever can commonly mimic systemic diseases, leading to several immunological manifestations. Thrombotic micro-angiopathies manifest as a spectrum of related disorders in the form of thrombocytopenic purpura and hemolytic uremic syndrome.

Case Report: We report a 77-year-old woman, who presented an acquired thrombotic microangiopathy with renal expression associated with the presence of anti-ADAMTS 13 antibodies, which occurred during an acute infection by Coxiella burnetii (acute Q fever).

Conclusion: Auto-immune disorders are well-known in chronic or acute Q fever but to our knowledge, this is the first reported observation of thrombotic microangiopathy with anti-ADAMTS 13 antibodies.

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Source
http://dx.doi.org/10.1016/j.revmed.2012.08.012DOI Listing

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