Direct α-arylation of α-amino carbonyl compounds with indoles using visible light photoredox catalysis.

J Org Chem

State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, China.

Published: October 2012

A general and mild method for the construction of functionalized 2-(1H-indol-3-yl)-2-amino-carbonyl compounds was achieved, which represents the first example of direct α-arylation of α-amino carbonyl compounds with indoles using the visible light photoredox catalysis strategy.

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http://dx.doi.org/10.1021/jo301691hDOI Listing

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