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Cardiac sympathetic denervation and anxiety in Parkinson disease.
Parkinsonism Relat Disord
July 2024
Department of Neurology, University of Michigan, Ann Arbor, MI, USA; Functional Neuroimaging, Cognitive, and Mobility Laboratory, Department of Radiology, University of Michigan, Ann Arbor, MI, USA; Morris K. Udall Center of Excellence for Parkinson's Disease Research, University of Michigan, Ann Arbor, MI, USA; Department of Radiology, University of Michigan, Ann Arbor, MI, USA; Parkinson's Foundation Research Center of Excellence, University of Michigan, Ann Arbor, MI, USA; Neurology Service and GRECC, VA Ann Arbor Healthcare System, Ann Arbor, MI, USA.
Background: Anxiety in Parkinson disease (PD) negatively impacts quality of life. While research predominantly focuses on central nervous system changes, some evidence suggests a connection between peripheral autonomic dysfunctions and PD-related anxiety. The role of the peripheral autonomic nervous system in this context may be overlooked.
View Article and Find Full Text PDF[Cognitive impairment in multiple system atrophy - exclusion criteria or an integral part of the clinical picture?].
Zh Nevrol Psikhiatr Im S S Korsakova
May 2024
North Caucasian Multidisciplinary Medical Center, Beslan, Russia.
Multiple system atrophy (MSA) is a severe, orphan disease characterized by a steady increase in symptoms of parkinsonism, cerebellar disorders, and autonomic failure. In addition to autonomic failure, which is considered the defining symptom of this type of atypical parkinsonism, there are a range of other non-motor clinical manifestations, such as sleep disorders, pain syndrome, anxiety-depressive disorders, cognitive impairment (CI). CI, especially severe CI, has long been considered as a distinctive feature of MCA.
View Article and Find Full Text PDFAssociation between autonomic dysfunction with motor and non-motor symptoms in patients with Parkinson's disease.
J Neural Transm (Vienna)
April 2024
Parkinson Medical Center, Beijing Rehabilitation Hospital, Capital Medical University, Badachu, Xixiazhuang, Shijingshan District, Beijing, 100144, China.
To investigate the association between autonomic dysfunction (AutD) and motor as well as non-motor symptoms (NMS) in patients with Parkinson's disease (PD). Fifty-three PD patients were divided into two groups based on the number of domains affected by AutD: a multi-domain AutD group (AutD-M) and a single-domain AutD group (AutD-S), as evaluated using the Scale for Outcomes in Parkinson's disease-Autonomic (SCOPA-AUT), which assesses autonomic symptoms, one of the NMS. A comprehensive comparison was conducted between the two groups, including clinical measures such as clinical scales, quantitative evaluations of motor function and exercise capacity.
View Article and Find Full Text PDF[Anxiety-depressive symptoms in the structure of eating disorders in adolescents].
Zh Nevrol Psikhiatr Im S S Korsakova
December 2023
Razumovsky Saratov State Medical University, Saratov, Russia.
Objective: To identify the features of anxiety and depressive disorders in adolescents with eating disorders (ED) in a comprehensive approach to treatment.
Material And Methods: The study included 30 middle-aged (11-14 years) and older female adolescents (15-18 years) with ED. All patients underwent psychotherapy using a cognitive-behavioral approach 2 times a week, as well as psychopharmacotherapy using SSRI antidepressants (fluvoxamine, sertraline).
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Post-COVID Syndrome: A Common Neuroimmune Ground?
Diagnostics (Basel)
December 2022
Laboratory of the Mosaic of Autoimmunity and Department of Pathology, Saint Petersburg State University, 199034 Saint-Petersburg, Russia.
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating chronic disease of unknown etiology, sharing a similar clinical presentation with the increasingly recognized post-COVID syndrome. We performed the first cross-sectional study of ME/CFS in a community population in Russia. Then we described and compared some clinical and pathophysiological characteristics of ME/CFS and post-COVID syndrome as neuroimmune disorders.
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