Background: Several methods have been developed to reduce the radiation dose in coronary computed tomography angiography (CTA).
Objective: The objective of our study was to evaluate the effects of Adaptive Iterative Dose Reduction (AIDR) on objective and subjective image quality as well as the radiation dose, compared with conventional filtered back projection (FBP), in coronary CTA.
Methods: We retrospectively reviewed 100 consecutive patients who underwent coronary CTA. In the first 50 patients, a higher tube current was used, and images were reconstructed with FBP. In the last 50 patients, a lower tube current was used, and images were reconstructed with AIDR. Subjective and objective image quality (noise, signal-to-noise ratio, contrast-to-noise ratio) were assessed.
Results: The median radiation dose of the AIDR group was 22% lower than that of the FBP group (4.2 vs 5.4 mSv; P = 0.0001). No significant difference was found in subjective image quality, noise, signal-to-noise ratio, or contrast-to-noise ratio between the 2 groups.
Conclusion: AIDR reduced the tube current which resulted in reduction of radiation dose in coronary CTA while maintaining subjective and objective image quality compared with coronary CTA reconstructed with FBP.
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http://dx.doi.org/10.1016/j.jcct.2012.02.009 | DOI Listing |
Asian Pac J Cancer Prev
January 2025
Department of Physics, Faculty of Sciences, Arak University, Arak, Iran.
Objective: Addressing the rising cancer rates through timely diagnosis and treatment is crucial. Additionally, cancer survivors need to understand the potential risk of developing secondary cancer (SC), which can be influenced by several factors including treatment modalities, lifestyle choices, and habits such as smoking and alcohol consumption. This study aims to establish a novel relationship using linear regression models between dose and the risk of SC, comparing different prediction methods for lung, colon, and breast cancer.
View Article and Find Full Text PDFMed Phys
January 2025
Institut Curie, Université PSL, CNRS UMR3347, Inserm U1021, Signalisation Radiobiologie et Cancer, Orsay, France.
Background: Breast cancer is the leading cause of female cancer mortality worldwide, accounting for 1 in 6 cancer deaths. Surgery, radiation, and systemic therapy are the three pillars of breast cancer treatment, with several strategies developed to combine them. The association of preoperative radiotherapy with immunotherapy may improve breast cancer tumor control by exploiting the tumor radio-induced immune priming.
View Article and Find Full Text PDFMed Phys
January 2025
OncoRay - National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany.
Background: Previous studies have shown that in-beam magnetic resonance imaging (MRI) can be used to visualize a proton beam during the irradiation of liquid-filled phantoms. The beam energy- and current-dependent local image contrast observed in water was identified to be predominantly caused by beam-induced buoyant convection and associated flow effects. Besides this flow dependency, the MR signal change was found to be characterized by a change in the relaxation time of water, hinting at a radiochemical contribution, which was hypothesized to lie in oxygen depletion-evoked relaxation time lengthening.
View Article and Find Full Text PDFEnviron Sci Pollut Res Int
January 2025
Programa de Pós-Graduação Em Saneamento, Meio Ambiente E Recursos Hídricos, Departamento de Engenharia Sanitária E Ambiental, Universidade Federal de Minas Gerais, Av. Antonio Carlos 6627, Belo Horizonte, MG, 31270-901, Brazil.
Wastewater treatment plants (WWTPs) currently face major challenges toward the removal of microcontaminants and/or microbial matrices and consequently play an important role in the potential dissemination of biological resistance in freshwater. The ultraviolet (UV) system is a tertiary treatment strategy increasingly applied worldwide, although many studies have shown that disinfected effluent can still contain antibiotic-resistant bacteria and resistance genes. Therefore, to better understand the effects of UV radiation doses on the removal of all resistance elements (antibiotics, antibiotic-resistant bacteria, and antibiotic resistance genes), the present study was designed using a pilot-scale photoreactor.
View Article and Find Full Text PDFRadiat Environ Biophys
January 2025
Department of Radiation Oncology, Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Manipal, India.
Goal of the present study was to develop and build a phantom that replicates the air gaps under a gel bolus and to estimate the surface dose (D) under normal incidence with a 6 MV photon beam. For this, an acrylic phantom with 10 plates, each including five open slots (one in the centre and four off axis) with a size of 2 cm × 2 cm at depths of 0.54 cm, 0.
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