Cyclosporine-induced haemolysis is a very rare adverse reaction. The few published cases in the literature are described in the context of haemolytic-uraemic syndrome in transplanted patients. We report a case of cyclosporine-induced haemolytic anaemia in a 9-year-old girl being treated for severe dermatomyositis.
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http://dx.doi.org/10.1136/bcr-2012-006736 | DOI Listing |
J Vet Intern Med
July 2016
Department of Clinical Sciences, College of Veterinary Medicine, Mississippi State University, MS, 39762-6100.
Background: Cyclosporine increases thromboxane synthesis in dogs, potentially increasing the thrombogenic properties of platelets.
Hypothesis/objectives: Our hypothesis was that the concurrent administration of low-dose aspirin and cyclosporine would inhibit cyclosporine-associated thromboxane synthesis without altering the antiplatelet effects of aspirin. The objective was to determine the effects of cyclosporine and aspirin on primary hemostasis.
J Am Soc Nephrol
November 2013
Department of Medicine and.
Defective control of the alternative pathway of complement is an important risk factor for several renal diseases, including atypical hemolytic uremic syndrome. Infections, drugs, pregnancy, and hemodynamic insults can trigger episodes of atypical hemolytic uremic syndrome in susceptible patients. Although the mechanisms linking these clinical events with disease flares are unknown, recent work has revealed that each of these clinical conditions causes cells to release microparticles.
View Article and Find Full Text PDFBMJ Case Rep
September 2012
Hospital Dona Estefânia, Lisboa, Portugal.
Cyclosporine-induced haemolysis is a very rare adverse reaction. The few published cases in the literature are described in the context of haemolytic-uraemic syndrome in transplanted patients. We report a case of cyclosporine-induced haemolytic anaemia in a 9-year-old girl being treated for severe dermatomyositis.
View Article and Find Full Text PDFTransfusion
July 2009
Department of Transfusion Medicine, Warren G. Magnuson Clinical Center, National Institutes of Health, Bethesda, MD 20892-1184, USA.
Transplant Proc
September 2004
Department of Urology and Renal Transplantation, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India.
Purpose: Although mycophenolate mofetil (MMF) has emerged as a valuable immunosuppressive in renal transplantation, its high cost demands that it be used selectively.
Materials And Methods: This retrospectively study included 55 renal transplant patients on MMF for rescue therapy after treatment of acute vascular rejection (n = 45), acute/chronic liver disease with elevated transaminases (n = 4), early chronic rejection (n = 2), cyclosporine toxicity (n = 3), and cyclosporine-induced hemolytic-uremic syndrome (n = 1). The patients were given 1.
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