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High pressure processing at different hydration levels as a tool to enhance rice bran stability and techno-functionality.

Food Res Int

February 2025

Institute of Agrochemistry and Food Technology (IATA-CSIC), Carrer del Catedràtic Agustín Escardino Benlloch, 7, 46980 Paterna, Valencia, Spain; Department of Food and Human Nutritional Sciences, University of Manitoba. Winnipeg, Canada. Electronic address:

High-pressure processing (HPP) enhances food safety and shelf life by inactivating microorganisms and preserving food quality, yet its effectiveness in low-humidity environments has not been evaluated. This study investigated the effects of HPP at 500 MPa for 15 min across varying hydration levels (15, 30, 60, 77 %) on rice bran (RB), aiming to identify microbial effectiveness, besides techno-functional and physicochemical properties. HPP effectively reduced mesophilic bacteria, molds and yeast of RB at > 15 % hydration level, achieving reductions of up to 4 logarithmic cycles in the latter, nearing the detection limit of the method.

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The development of aqueous zinc metal batteries (AZMBs) is hampered by dendrites and side reactions induced by reactive HO. In this study, a hydrated eutectic electrolyte with restrictive water consisting of zinc trifluoromethanesulfonate (Zn(OTf)), 1,3-propanediol (PDO), and water is developed to improve the stability of the anode/electrolyte interface in AZMBs via the formation of a water-deficient interface. Additionally, PDO participates in the Zn solvation structure and inhibits the movement of water molecules.

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Norcantharidin (NCTD), an antitumor agent with an increased leukocyte function, has been used for the treatment of hepatocellular carcinoma (HCC) in clinical. However, the clinical application of NCTD is limited due to its inadequate hydrophilicity and lipophilicity, short half-life (t), as well as adverse effects such as vascular irritation, cardiotoxicity, and nephrotoxicity. Herein, a lactoferrin (Lf) and DSPE-mPEG functionalized liposomes loaded with norcantharidic acid (NCA), an active metabolite of NCTD, was constructed for the targeted therapy of HCC.

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Conjugation of PDLA onto MgO microspheres: comparison between solution grafting and melt grafting methods.

J Mater Chem B

January 2025

Engineering Research Centre for Biomedical Materials of Ministry of Education, Key Laboratory for Ultrafine Materials of Ministry of Education, Key Laboratory for Ultrafine Materials of Ministry of Education, School of Materials Science and Engineering, East China University of Science and Technology, Shanghai, 200237, China.

Magnesium oxide (MgO) is known for its bioactivity and osteoconductivity when incorporated into biodegradable poly(lactic acid) (PLA), whereas the weak interfacial bonding between MgO microspheres (mMPs) and PLA often leads to suboptimal composite properties with uncontrollable functionality. Conjugation of mMPs with PLA may offer a good way to enhance their compatibility. In this study, we systematically investigated two grafting techniques, solution grafting (Sol) and melt grafting (Mel), to decorate poly (D-lactic acid) (PDLA) on mMPs pre-treated by prioritized hydration to obtain Sol MPs and Mel MPs, in order to optimize the grafting efficiency and improve their controllability in the properties including the crystal structure and surface morphology.

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