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Development of a multi-epitope chimeric vaccine in silico against Babesia bovis, Theileria annulata, and Anaplasma marginale using computational biology tools and reverse vaccinology approach.
PLoS One
January 2025
Department of Pathology and Parasitology, Chittagong Veterinary and Animal Sciences University (CVASU), Chittagong, Bangladesh.
The three rickettsial parasites- Babesia bovis, Theileria annulata and Anaplasma Marginale are responsible for causing Babesiosis, Theileriosis and Anaplasmosis among cattle. These diseases exist due to spreading of infected ticks. A large number of cattle were found to suffer from mixed infections caused by the three parasites at the same time.
View Article and Find Full Text PDFPrevalence of Theileria Equi and Babesia Caballi and Associated Hemato-Biochemical Changes in Racing Horses in Erbil Province, Iraq.
Acta Parasitol
January 2025
Department of Biology, College of Sciences, Salahaddin University-Erbil, Erbil, Kurdistan Region, Iraq.
Purposes: This study aimed to determine the prevalence of Theileria equi (T. equi) and Babesia caballi (B. caballi) in racing horses in Erbil Province, Iraq, and to assess the associated hemato-biochemical changes in infected animals.
View Article and Find Full Text PDFVesicular mechanisms of drug resistance in apicomplexan parasites.
Microbiol Mol Biol Rev
January 2025
Special Centre for Molecular Medicine, Jawaharlal Nehru University, New Delhi, India.
Vesicular mechanisms of drug resistance are known to exist across prokaryotes and eukaryotes. Vesicles are sacs that form when a lipid bilayer 'bends' to engulf and isolate contents from the cytoplasm or extracellular environment. They have a wide range of functions, including vehicles of communication within and across cells, trafficking of protein intermediates to their rightful organellar destinations, and carriers of substrates destined for autophagy.
View Article and Find Full Text PDFA novel genotype of Babesia microti-like group in Ixodes montoyanus ticks parasitizing the Andean bear (Tremarctos ornatus) in Ecuador.
Exp Appl Acarol
January 2025
Laboratorio de Vectores y Enfermedades Transmitidas, Departamento de Ciencias Biológicas, CENUR Litoral Norte, Universidad de la República, Salto, Uruguay.
Babesia species (Piroplasmida) are hemoparasites that infect erythrocytes of mammals and birds and are mainly transmitted by hard ticks (Acari: Ixodidae). These hemoparasites are known to be the second most common parasites infecting mammals, after trypanosomes, and some species may cause malaria-like disease in humans. Diagnosis and understanding of Babesia diversity increasingly rely on genetic data obtained through molecular techniques.
View Article and Find Full Text PDFApplication of molecular approach in combination with providing treatment and control measures for combating and infections in small scale livestock farms in Thailand.
Parasite Epidemiol Control
February 2025
Department of Parasitology, Faculty of Veterinary Medicine, Kasetsart University, Lad Yao, Chatuchak, Bangkok 10900, Thailand.
Bovine babesiosis is a tick-borne disease that is caused by apicomplexan protozoan parasite in the genus of infections affect cattle health, reduce milk and meat production and lead to economic losses in tropical and subtropical countries. parasites are difficult to diagnose in the early stage of infections during low parasitemia and asymptomatic conditions led to the lack of treatment and control at the early stage of infection. This study aimed to integrate a molecular tool for the detection and genetic characterization of in small-scale livestock farming in Thailand, and to study the risk factors association with infections in small scale livestock farms in Thailand.
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