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This is a case report of spontaneous haemoperitoneum caused by ruptured utero-ovarian vessels during the third trimester of pregnancy. The patient presented with acute abdominal pain and hypotension twice to the emergency room. The initial diagnosis was placental abruptio and the patient had emergency caesarean section. There was utero-ovarian plexus laceration and suture-ligation was performed. The maternal outcome was good. The infant had birth asphyxia and was extubated on the third day. Both mother and infant were discharged in good condition.
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http://dx.doi.org/10.1136/bcr-2012-007113 | DOI Listing |
Int J Mol Sci
March 2025
Research Institute, Medical University of Plovdiv, 15A Vasil Aprilov Blvd., 4002 Plovdiv, Bulgaria.
(NS) is a promising medicinal plant with diverse therapeutic properties. This study aimed to investigate the impact of NS oil (NSO) on memory functions in rats with LPS (lipopolysaccharide)-induced neuroinflammation, as well as its effect on serum levels of inflammatory cytokines, neuropeptide Y (NPY) and brain-derived neurotrophic factor (BDNF). Male rats were divided into four groups: control, LPS-control, LPS+NSO 3 and 5 mL/kg.
View Article and Find Full Text PDFInt Immunopharmacol
March 2025
Department of Pharmacology, The Key Laboratory of Neural and Vascular Biology, Ministry of Education, The Key Laboratory of New Drug Pharmacology and Toxicology, Center of Innovative Drug Research and Evaluation, Hebei Medical University, Shijiazhuang 050000, China. Electronic address:
Background: Discovering lead compounds with anti-inflammatory and analgesic activities from natural products with minimal toxic side effects has been a long-term goal for researchers. 4-Methylesculetin (4-ME), a natural coumarin derivative, has been reported to have anti-inflammatory and antioxidant properties, but its analgesic effect has not yet been studied. This research investigates the analgesic effect and underlying mechanism of 4-ME in peripheral inflammatory pain.
View Article and Find Full Text PDFBrain Res Bull
February 2025
Department of Pediatrics, Renmin Hospital of Wuhan University, Wuhan, China.
Background: Two key factors associated with the comorbidity of epilepsy and depression (EAD), activity regulated cytoskeletal protein (Arc) and homer protein homolog 1 (Homer1), were previously identified by our group through bioinformatics methods (Yu et al., 2022). The expression of Arc and Homer1 were verified through animal experiments.
View Article and Find Full Text PDFBrain Res Bull
February 2025
Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA; Division of Sleep Medicine, Harvard Medical School, Boston, MA, USA. Electronic address:
Background: The brain requires a continuous fuel supply to support cognition and can get energy from glucose and ketones. Dysregulated brain metabolism is thought to contribute to perioperative neurocognitive disorders and anesthesia-induced burst suppression. Therefore, we investigated the relationship between brain metabolites and neurophysiology during the behavioral states of sleep and anesthesia under a standard diet (SD) or a ketogenic diet (KD).
View Article and Find Full Text PDFIDCases
January 2025
University of Tunis El Manar, Department of General Surgery, Trauma Center Ben Arous, Tunisia.
Spontaneous intraperitoneal rupture of hepatic hydatid cysts is a rare but serious complication that can lead to significant morbidity and mortality due to risks such as anaphylactic shock and secondary peritoneal hydatidosis. This report presents the case of a 59-year-old male farmer from a rural area of Tunisia who presented with severe abdominal pain, nausea, and vomiting. Diagnostic imaging revealed a large hepatic cyst with free peritoneal fluid, indicating a ruptured hydatid cyst.
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