Treatment options for large, compressive goiters are currently limited to surgery and radioiodine administration. Classically, the first-line option has been surgery, with radioiodine therapy being reserved as an alternative treatment in patients with high surgical risk. We describe the case of an 81-year-old woman with a large, compressive multinodular goiter and hyperthyroidism, substernal extension and associated co-morbidity, contraindicating surgery. We review the efficacy of different treatment options for compressive multinodular goiter, as well as the potential secondary complications.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/S1575-0922(08)70681-8 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Incidental Thyroid Goiter with Large Posterior Mediastinal Extension: A Case Report.
Indian J Otolaryngol Head Neck Surg
February 2025
ENT Department, Wrightingtington, Wigan and Leigh NHS Foundation Trust, Wigan, UK.
Mediastinal goiters represent descent of thyroid tissue from the neck to the intra thoracic cavity most commonly in the anterior mediastinal compartment. Posterior mediastinal extension is uncommon, comprising only 10-15% of all mediastinal goiters. Thyroid masses within mediastinum may present with range of symptoms from being asymptomatic to severe compressive symptoms according to size and location.
View Article and Find Full Text PDFTracheomalacia in patients undergoing thyroid surgery-What is the true estimate: A systematic review and meta-analysis.
World J Otorhinolaryngol Head Neck Surg
March 2025
Department of Otolaryngology Queen Elizabeth Hospital Birmingham UK.
Objectives: Tracheomalacia is defined as the weakening of the tracheal rings secondary to long-standing compression or inherent structural weakness, leading to stridor and airway compromise. The common etiological factor of tracheomalacia includes compression of the tracheal framework due to a large multinodular goiter. There are various management techniques described in the literature to manage a patient with tracheomalacia including tracheostomy, tracheal stenting, and tracheopexy.
View Article and Find Full Text PDFMultinodular benign goitre as an immediate threat to the airway: a case report.
J Surg Case Rep
February 2025
Department of General Surgery, Unidade Local de Saúde Viseu Dão-Lafões, Avenida Rei Dom Duarte, 3504-509, Viseu, Portugal.
Acute upper airway obstruction (AUAO) due to benign thyroid disease is a rare but life-threatening condition. We report a case of an 82-year-old woman with a toxic multinodular goitre who presented to the emergency department with confusion and noisy breathing. Despite being initially stable, she developed progressive stridor and hypoxemia.
View Article and Find Full Text PDFPrimary Follicular Lymphoma of Thyroid: A Rare Case Report with Review of the Literature.
Iran J Pathol
October 2024
Department of Pathology, Jubilee Mission Medical College, KUHS, Thrissur, Kerala, India.
Background & Objective: Thyroid lymphomas are predominantly secondary to lymphoma at other sites, and primary follicular lymphoma of the thyroid is a very rare entity.
Case Presentation: Here, we report a case of a 62-year-old female who presented with swelling in the front of her neck for one month. The clinical diagnosis was a multinodular goiter.
Medical eyes on art: describing multinodular Goiter in Nicolini's Statue at the Aula Magna of University of Messina.
J Endocrinol Invest
February 2025
University of Messina, Messina, Italy.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!