The purpose of this study is to compare two types of sequences in brain magnetic resonance (MR) examinations of uncooperative and cooperative patients. For each group of patients, the pairs of sequences that were compared were two T2-weighted (T2-W) fluid attenuated inversion recovery sequences with different k-space trajectories (conventional Cartesian and BLADE) and two T2-TSE weighted with different k-space trajectories (conventional Cartesian and BLADE). Twenty-three consecutive uncooperative patients and 44 cooperative patients, who routinely underwent brain MR imaging examination, participated in the study. Both qualitative and quantitative analyses were performed based on the signal-to-noise ratio, contrast-to-noise ratio (CNR), and relative contrast (ReCon) measures of normal anatomic structures. The qualitative analysis was performed by experienced radiologists. Also, the presence of motion, other (e.g., Gibbs, susceptibility artifacts, phase encoding from vessels) artifacts and pulsatile flow artifacts was evaluated. In the uncooperative group of patients, BLADE sequences were superior to the corresponding conventional sequences in all the cases. Furthermore, the differences were found to be statistically significant in almost all the cases. In the cooperative group of patients, BLADE sequences were superior to the conventional sequences with the differences of the CNR and ReCon values in nine cases being statistically significant. Furthermore, BLADE sequences eliminated motion and other artifacts and T2 FLAIR BLADE sequences eliminated pulsatile flow artifacts. BLADE sequences (T2-TSE and T2 FLAIR) should be used in brain MR examinations of uncooperative patients. In cooperative patients, T2-TSE BLADE sequences may be used as part of the routine protocol and orbital examinations. T2 FLAIR BLADE sequences may be used optionally in examinations of AVM, orbits, haemorrhages, ventricular lesions, lesions in the frontal lobe, periventricular lesions, lesions in regions close to artifacts and lesions in posterior fossa.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.mri.2012.08.001 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Amino acid substrate specificities and tissue expression profiles of the nine CYP79A encoding genes in Sorghum bicolor.
Physiol Plant
January 2025
Plant Biochemistry Laboratory, Department of Plant and Environmental Sciences, University of Copenhagen, Frederiksberg C, Copenhagen, Denmark.
Cytochrome P450s of the CYP79 family catalyze two N-hydroxylation reactions, converting a selected number of amino acids into the corresponding oximes. The sorghum genome (Sorghum bicolor) harbours nine CYP79A encoding genes, and here sequence comparisons of the CYP79As along with their substrate recognition sites (SRSs) are provided. The substrate specificity of previously uncharacterized CYP79As was investigated by transient expression in Nicotiana benthamiana and subsequent transformation of the oximes formed into the corresponding stable oxime glucosides catalyzed by endogenous UDPG-glucosyltransferases (UGTs).
View Article and Find Full Text PDFFirst Report of Causing Rot of Potato in China.
Plant Dis
January 2025
Institute of Urban Agriculture, Chinese Academy of Agricultural Sciences,, Chengdu, China;
Potato ( L.) is the third largest food crop globally following rice and wheat, which is consumed by more than 1 billion people worldwide (FAO 2024). In October 2022, tuber rot of potato (cv.
View Article and Find Full Text PDFBackground: When antispasmodics are unavailable, the periodically rotated overlapping parallel lines with enhanced reconstruction (PROPELLER; called BLADE by Siemens Healthineers) or half Fourier single-shot turbo spin echo (HASTE) is clinically used in gynecologic MRI. However, their imaging qualities are limited compared to Turbo Spin Echo (TSE) with antispasmodics. Even with antispasmodics, TSE can be artifact-affected, necessitating a rapid backup sequence.
View Article and Find Full Text PDFUnveiling the structural and functional perspectives of a bifunctional α-l-arabinofuranosidase/endo-β-1,4-xylanase (BoGH43_35) from Bacteroides ovatus.
Arch Biochem Biophys
November 2024
Carbohydrate Enzyme Biotechnology Laboratory, Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati, Assam, 781039, India. Electronic address:
Article Synopsis
- - Arabinoxylan, a complex sugar, can be broken down by enzymes like α-l-arabinofuranosidase and xylanase; a new bifunctional enzyme (BoGH43_35) from Bacteroides ovatus has been studied for its ability to degrade these sugars.
- - The enzyme's structure features a stable 5-bladed β-propeller fold and carbohydrate-binding modules, with molecular dynamics confirming its compactness and stability during simulations.
- - Binding affinity analysis showed BoGH43_35 has the strongest interaction with arabinose and maintains stability in its complex forms, along with measurements suggesting good solubility and low aggregation in solution.
Automated lung segmentation on chest MRI in children with cystic fibrosis.
Front Med (Lausanne)
November 2024
Institute of Medical Informatics, Heidelberg University, Heidelberg, Germany.
Article Synopsis
- Segmentation of lung structures in medical imaging is important for diagnosing and treating diseases like cystic fibrosis, with neural networks showing better results than traditional methods, but challenges remain with different imaging types and pathologies.
- This study used deep learning to segment MRI scans from pediatric cystic fibrosis patients, employing the nnU-Net framework and analyzing data from 165 scans across various sequences (BLADE, VIBE, HASTE). The analysis focused on patient variability in disease severity and age.
- Results indicated high segmentation accuracy (with Dice coefficients around 0.95-0.96) and consistent performance regardless of patient differences, although some issues with segmentation completeness were noted, particularly in the diaphragm area; the model also showed
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!