A case of bupropion-induced stuttering.

Gen Hosp Psychiatry

Department of Clinical Sciences, The Commonwealth Medical College, Scranton, PA 17701, USA. Electronic address:

Published: April 2014

Objective: Stuttering is a frequent side effect of many psychotropic drugs, particularly antidepressants.

Method: This is a case report of a woman presenting with stuttering after starting bupropion treatment for her depression.

Results: The patient's stuttering resolved after discontinuing the bupropion.

Conclusion: Neuroimaging and pharmacological studies have implicated dopamine in the pathophysiology of stuttering. Bupropion's ability to increase dopamine in the frontal cortex was suspected to have been involved in this patient's stuttering. However, further research is needed before causality can be assured.

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Source
http://dx.doi.org/10.1016/j.genhosppsych.2012.07.003DOI Listing

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