Zoonoses constitute 868 (61%) of all known infectious diseases, 75% of the infections considered 'emerging' are zoonoses. Developed nations have national programmes, adjoining "One Health" concept to combat zoonoses, whereas inadequacies exist in developing nations. As a case study, role of national programmes in India, a developing nation with a large human and animal population, was explored, as we did have acquaintance of it. Data from PubMed was extracted using keywords "Zoonoses AND Prevalence/Incidence AND India AND Human OR Animal" till 2009. Additionally, some individual disease keywords were used for extraction, which were missed by the above comprehensive search terms. On appraisal, the health sector in India has only a few national programme on zoonoses where as none exists in animal husbandry sector. In the struggle against zoonoses -a major constituent of emerging infections, a system approach based, one national programme is urgently required for the developing world.

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