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Chromatin 'resetting' during transcription elongation: a central role for methylated H3K36. | LitMetric

Chromatin 'resetting' during transcription elongation: a central role for methylated H3K36.

Nat Struct Mol Biol

Department of Molecular Carcinogenesis at The Virginia Harris Cockrell Cancer Research Center, University of Texas MD Anderson Cancer Center, Smithville, Texas, USA.

Published: September 2012

A number of events must occur to preserve the integrity of the chromatin template during gene transcription. A study in this issue reveals a novel mechanism whereby chromatin remodelers are recruited to histone modifications within gene bodies to prevent aberrant histone exchange during transcriptional elongation.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657557PMC
http://dx.doi.org/10.1038/nsmb.2370DOI Listing

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