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Sarcoidosis presenting as massive splenic infarction. | LitMetric

Sarcoidosis presenting as massive splenic infarction.

Case Rep Rheumatol

Rheumatology Department, Wexham Park Hospital, Heatherwood and Wexham Park Hospitals NHS Foundation Trust, Wexham, Slough, Berkshire SL2 4HL, UK.

Published: September 2012

AI Article Synopsis

  • Sarcoidosis is a complex disease characterized by granulomatous inflammation affecting multiple body systems, with common involvement of the spleen, leading to splenomegaly.
  • Despite being associated with enlarged spleen, massive splenomegaly is quite rare and can sometimes cause complications like splenic infarction.
  • This report documents a unique case of a woman experiencing massive splenic infarction linked to sarcoidosis, confirmed by granulomatous liver inflammation.

Article Abstract

Sarcoidosis is a multisystem granulomatous disease of unknown aetiology. Granulomatous inflammation involving the spleen is common and associated with splenomegaly. However, massive splenomegaly is a rare occurrence. Infrequently massive splenomegaly can result in splenic infarction. Massive splenic infarction in sarcoidosis has, to our knowledge, not been previously reported. We present a case of a woman presenting with massive splenic infarction and sarcoidosis confirmed by granulomatous inflammation of the liver.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420793PMC
http://dx.doi.org/10.1155/2012/834758DOI Listing

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