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http://dx.doi.org/10.1093/infdis/jis550 | DOI Listing |
J Infect Public Health
December 2024
Biomedical Research Center, QU Health, Qatar University, PO Box 2713, Doha, Qatar. Electronic address:
Background: Human herpesvirus 8 (HHV-8) is a critical causative agent behind Kaposi sarcoma (KS), an oncogenic disease with profound consequences in immunocompromised individuals. Studies suggested HHV-8 seroprevalence in healthy populations is uncommon, but comprehensive investigations within the Middle East region remain scarce. This study aimed to bridge this knowledge gap by meticulously assessing HHV-8 seroprevalence among healthy blood donors in Qatar, leveraging serological methodologies and PCR.
View Article and Find Full Text PDFObjectives: Human herpesvirus 8 (HHV8) is rarely studied in Congo, despite its prevalence in Africa. Among healthy individuals, HHV-8 does not always lead to a life-threatening infection; however, in immunocompromised individuals, it could lead to more severe disease. The distribution of HHV-8 genotypes varies depending on ethnicity and geographic region.
View Article and Find Full Text PDFCureus
March 2024
Internal Medicine, Centro Hospitalar de Trás-os-Montes e Alto Douro, Chaves, PRT.
Cureus
February 2024
Medicine, Faculdade de Medicina da Universidade do Porto (FMUP), Porto, PRT.
Multicentric Castleman disease (MCD) is a poorly understood, heterogeneous lymphoproliferative disorder with benign hyperplastic lymph nodes and systemic inflammatory symptoms. Human herpesvirus-8 (HHV-8) may be associated with MCD, whether or not the patient is infected with the human immunodeficiency virus (HIV). A 74-year-old man presented with anaemia, thrombocytopenia and bilateral axillary adenomegaly of unknown origin.
View Article and Find Full Text PDFAfr Health Sci
March 2023
Université de Sousse, Faculté de Médecine de Sousse, Laboratoire de Microbiologie, UR12SP34, Hôpital Farhat Hached,4000, Sousse,Tunisie.
Background: Human herpesvirus 8 (HHV-8) has been linked to the development of Kaposi's sarcoma (KS)and multiple other hematologic malignant disorders. However, the role of HHV-8 in acute leukemia patients is unknown.
Objectives: The objective of this study was to determine the prevalence of HHV-8 in Tunisian acute leukemia patients and in healthy blood donors.
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