The study of content of cerebral natriuretic propeptide (NT-proBNP) in patients with hemorrhagic fever and renal syndrome was carried out considering severity degree, period of disease, presence of clinical roentgenological signs of lungs affection. It is demonstrated that in patients with mild and severe degree of disease the content of NT-proBNP is reliably higher than in the control group and gets its peak values in oliguric period The indices of NT-proBNP are reliably higher in patients with clinical roentgenological signs of lungs affection as compared with patients without such signs. The correlation analysis revealed direct dependence between the content of NT-proBNP and systolic blood pressure in pulmonary artery in in patients with hemorrhagic fever and renal syndrome of mild severity

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