AI Article Synopsis
- The study aimed to identify factors affecting the increase in blood flow velocity in the superior mesenteric artery (SMA BFV) in infants after birth.
- Researchers measured SMA BFV in 35 premature infants over the first two weeks of life and found significant variability in blood flow.
- Key findings indicated that higher enteral feeding volumes led to greater increases in SMA BFV, while positive pressure ventilation or hyperalimentation resulted in lower increases.
Article Abstract
Objective: To identify factors related to the postnatal increase in superior mesenteric artery blood flow velocity (SMA BFV).
Study Design: SMA BFV was measured in 35 infants (birth weight 1047±246 g) on day of life (DOL) 1, 3, 5, 7 10 and 14. Latent curve modeling (LCM) was used to measure the longitudinal change in BFV for each subject, and the correlation between changes in BFV and baseline values. Non-parametric correlations were calculated between BFV and variables previously reported to be related to SMA BFV.
Results: There was significant variability in SMA BFV on DOL 1, a significant increase from DOL 1-14, and significant variability in the postnatal increase. Infants with higher enteral feeding volumes had greater increases, while infants receiving positive pressure ventilation or hyperalimentation had lower increases.
Conclusions: Several clinical factors affect the postnatal increase in SMA BFV. The use of LCM is useful in longitudinal studies of very low birth weight (VLBW) infants, who are clinically and demographically heterogeneous.
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| http://dx.doi.org/10.1515/jpm-2011-0235 | DOI Listing |
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