Management of myelofibrosis: a survey of current practice in the United Kingdom.

Aims: To investigate the experience of clinicians in the management of patients with myelofibrosis, current treatment options and their utility.

Methods: We used an internet-based survey

Results: Of 105 respondents (mostly consultants), 79% identified bothersome symptoms as the most common issue to be addressed, while for 19%, lack of efficacy of treatment fell into this category. The survey found that a wide variety of treatments are employed but with poor perceived efficacy.

Conclusions: This is the first UK based assessment of management of myelofibrosis. Perspectives may evolve with the inception of novel therapeutics in this field , but clinical guidelines for effective management currently recommend a wide variety of agents and suggest a limited likely success rate.