A case of hyperprolactinemia, probably induced by eletriptan.

Int J Clin Pharmacol Ther

Department of Endocrinology and Metabolism, Diskapi Yildirim Beyazit Education and Researching Hospital, Ankara, Turkey.

Published: December 2012

AI Article Synopsis

  • A 25-year-old woman starts using eletriptan for her severe migraines and experiences oligomenorrhea (irregular menstruation) and galactorrhea (milk production) a month later.
  • All other potential causes of elevated prolactin levels were dismissed.
  • This case is the first documented instance of hyperprolactinemia linked to eletriptan use, suggesting a possible connection according to the Naranjo probability scale.

Article Abstract

A 25-year-old woman with a severe migraine begins to use a migraine specific agent, eletriptan (40 mg/d). One month later, she had oligomenorrhea and galactorrhea. We ruled out all causes of hyperprolactinemia. To our knowledge, this is the first published postmarketing case report of eletriptan- induced hyperprolactinemia, presented as oligomenorrhea and galactorrhea in a patient. The Naranjo probability scale indicates a probable relationship between hyperprolactinemia and eletriptan therapy.

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Source
http://dx.doi.org/10.5414/CP201744DOI Listing

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