Synthesis of fluorenone derivatives through Pd-catalyzed dehydrogenative cyclization.

Org Lett

Beijing National Laboratory of Molecular Sciences (BNLMS), College of Chemistry and Green Chemistry Center, Peking University, Beijing 100871, China.

Published: September 2012

Palladium-catalyzed dual C-H functionalization of benzophenones to form fluorenones by oxidative dehydrogenative cyclization is reported. This method provides a concise and effective route toward the synthesis of fluorenone derivatives, which shows outstanding functional group compatibility.

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http://dx.doi.org/10.1021/ol302181zDOI Listing

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