Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1111/j.1538-7836.2012.04911.x | DOI Listing |
J Thromb Haemost
November 2012
Mammalian Cell Technology Protein Purification Exploratory ADME Biopharmaceuticals, Novo Nordisk A/S, Måløv, Denmark.
Prilozi
July 2007
Department of Nephrology, Endocrinology and Metabolic Diseases, Medical University of Silesia, Katowice, Poland.
There are several new erythropoiesis stimulating agents that may potentially improve in the near future the management of anaemia in patients with chronic kidney disease. Some of the new erythropoiesis stimulating agents were synthesised by modification of the aminoacide sequence of the erythropoietin (EPO) molecule and hyperglycosylation and therefore they have improved pharmacokinetics (darbopoietin or CERA) by prolongation of the serum elimination half-life compared to epoietins. These agents may be administered less frequently with better stabilisation of blood haemoglobin concentration.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!