Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.5694/mja12.10047 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Meaningful Engagement as a Cornerstone for Implementing the Key Recommendations to Advance the Sexual and Reproductive Health and Rights of Women Living With HIV Across Policy, Practice, and Research in Canada.
J Int Assoc Provid AIDS Care
January 2025
Faculty of Health Sciences, Simon Fraser University, Vancouver BC, Canada.
In 2022, a community-academic collaborative team published 5 key recommendations for developing a national action plan to advance the sexual and reproductive health and rights (SRHR) of women living with HIV in Canada. In 2023, a national gathering was convened to strategize implementation of the recommendations across policy, practice, and research settings. Discussions highlighted that meaningful engagement of women living with HIV (recommendation 1) is foundational to implementing the other recommendations.
View Article and Find Full Text PDFBLOOD PROTEOMICS AND MULTIMODAL RISK PROFILING of human volunteers after incision injury: a translational study for advancing Personalized Pain Management After Surgery.
Pharmacol Res
January 2025
Department of Anaesthesiology, Intensive Care and Pain Medicine, University Hospital Muenster, Albert-Schweitzer-Campus 1, 44651 Muenster, Germany. Electronic address:
Article Synopsis
- A significant number of patients experience chronic pain after surgery, highlighting the urgent need for predictive models that consider bio-psycho-social and physiological factors.
- A study involving male volunteers assessed pain characteristics, psychological factors, and blood proteomics before and after an experimental incision to predict outcomes related to pain intensity and hyperalgesia.
- The results revealed that a combination of diverse parameters could predict pain responses more accurately than single features, identified specific protein signatures associated with inflammation, and suggested repurposing existing medications for better pain management.
Medication review interventions for adults living with advanced chronic kidney disease: A scoping review.
Br J Clin Pharmacol
December 2024
Department of Renal Medicine, University College London, London, UK.
Structured medication reviews (SMRs) were introduced into the National Health Service (NHS) Primary Care to support the delivery of the NHS Long-Term Plan for medicines optimization. SMRs improve the quality of care, reduce harm and offer value for money. However, evidence to support SMRs for patients with chronic kidney disease (CKD) stage G4-5D with elevated risk of cardiovascular disease and premature mortality is unknown.
View Article and Find Full Text PDFDeep proteomics and network pharmacology reveal sex- and age-shared neuropathic pain signatures in mouse dorsal root ganglia.
Pharmacol Res
January 2025
Division of Pharmacology and Toxicology, Department of Pharmaceutical Sciences, University of Vienna, Vienna, Austria. Electronic address:
Our understanding of how sex and age influence chronic pain at the molecular level is still limited with wide-reaching consequences for adolescent patients. Here, we leveraged deep proteome profiling of mouse dorsal root ganglia (DRG) from adolescent (4-week-old) and adult (12-week-old) male and female mice to investigate the establishment of neuropathic pain in the spared nerve injury (SNI)-model in parallel. We quantified over 12,000 proteins, including notable ion channels involved in pain, highlighting the sensitivity of our approach.
View Article and Find Full Text PDFSodium-glucose cotransporter 2 inhibitors for chronic kidney disease: Why, when and when not.
Aust J Gen Pract
December 2024
FRCP, FRACP, Consultant Physician, Department of General Medicine and Acute Assessment Unit, Canberra Hospital, Canberra, ACT; Clinical Associate Professor, Faculty of Health and Medical Sciences, University of Western Australia, Perth, WA; Associate Professor, ANU College of Health and Medicine, Australian National University, Canberra, ACT.
Background: Chronic kidney disease (CKD) is a significant healthcare problem. More advanced stages are associated with increased mortality, morbidity and cost. Instigating measures to slow down disease progression at an early stage can save lives, and millions of dollars of taxpayers' money.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!