For the first time the nature of cell damages under pseudotuberculosis as a generalized infection has been analyzed by positions of the modern knowledge about types of the cell death. The own and literature data have pointed to presence the apoptosis-induced effect of Yersinia pseudotuberculosis, a causative agent of this infection. In conclusion, the typical pathological changes for pseudotuberculosis infection such as granuloma formation with the central karyorrhexis could be appearance of apoptotic and secondary necrotic changes.

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