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Myelodysplastic Syndrome with t(1;7) Associated with Marked Dysmegakarypoiesis & Severe Thrombocytopenia: A Case Report and Review of the Literature. | LitMetric

AI Article Synopsis

  • A 70-year-old woman underwent a bone marrow exam to explore her low platelet count related to metastatic glucagonoma.
  • The examination revealed significant dysmegakaryopoiesis, leading to a diagnosis of refractory cytopenia with multilineage dysplasia.
  • An unusual cytogenetic change, t(1;7), was also identified, prompting a review of related literature on this specific lesion.

Article Abstract

We present the case of a 70-year-old woman who had a bone marrow examination performed to investigate marked thrombocytopenia in the context of a recent history of metastatic glucagonoma. Surprisingly this identified marked dysmegakaryopoiesis and fulfilled diagnostic criteria for refractory cytopenia with multilineage dysplasia, with a relatively uncommon associated cytogenetic lesion t(1;7). We present the case and review the literature of this cytogenetic lesion.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420701PMC
http://dx.doi.org/10.1155/2012/167653DOI Listing

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