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Highly Biocompatible Lamellar Liquid Crystals Based on Hempseed or Flaxseed Oil with Incorporated Betamethasone Dipropionate: A Bioinspired Multi-Target Dermal Drug Delivery System for Atopic Dermatitis Treatment.
Int J Nanomedicine
December 2024
Department of Pharmaceutical Technology, Faculty of Pharmacy, University of Ljubljana, Ljubljana, Slovenia.
Purpose: Atopic dermatitis (AD) is the most common chronic inflammatory skin disease that severely impairs patient's life quality and represents significant therapeutic challenge due to its pathophysiology arising from skin barrier dysfunction. Topical corticosteroids, the mainstay treatment for mild to moderate AD, are usually formulated into conventional dosage forms that are impeded by low drug permeation, resulting in high doses with consequent adverse effects, and also lack properties that would strengthen the skin barrier. Herein, we aimed to develop biomimetic lamellar lyotropic liquid crystals (LLCs), offering a novel alternative to conventional AD treatment.
View Article and Find Full Text PDFComparison of six different methods used in detection of colistin resistance in extensively drug-resistant K. pneumoniae, A. baumannii and P. aeruginosa isolates with the reference method broth microdilution method.
Eur J Clin Microbiol Infect Dis
December 2024
Faculty of Medicine, Department of Medical Microbiology, Sakarya University, Sakarya, Turkey.
Objective: This study aimed to evaluate the agreement of different methods with the reference method in the detection of colistin resistance in extensively drug-resistant K. pneumoniae, A. baumannii and P.
View Article and Find Full Text PDFComparison of Taxonomic Resolutions of Various Typing Methods for and Species Isolated from Landfill Leachate.
Indian J Microbiol
December 2024
Symbiosis Centre for Climate Change and Sustainability, Symbiosis International (Deemed University), Lavale, Pune, 412115 India.
Anaerobic bacteria and methanogenic archaea at municipal landfill dumping sites play a vital role in the landfill ecology, waste degradation, global warming and climate change. Although landfill works as a cheap way of solid waste management, unmanaged landfill plays a significant role in spreading pollutants and pathogens in natural ecosystems. The genera and are important groups of anaerobic microbes from a public and environmental health perspective.
View Article and Find Full Text PDFPrevalence, virulence factors and antifungal susceptibility of oral isolates of Candida albicans from patients with cystic fibrosis in Mexico.
Rev Iberoam Micol
December 2024
Universidad Autónoma de Nuevo León, Departamento de Microbiología, Facultad de Medicina y Hospital Universitario "Dr. José Eleuterio González", Monterrey, Mexico. Electronic address:
Background: Candida species are frequently isolated from the oral cavity of patients with cystic fibrosis. However, the information on the role of Candida in cystic fibrosis is scarce.
Aims: This study aimed to evaluate the prevalence, virulence profile and antifungal susceptibility of oral isolates of Candida albicans recovered from patients with cystic fibrosis.
Reported prevalence and comparison of diagnostic approaches for Candida africana: a systematic review with meta-analysis.
Diagn Progn Res
December 2024
The African Centre of Excellence in Bioinformatics and Data-Intensive Sciences, Infectious Diseases Institute, Makerere University, P.O. Box 22418, Kampala, Uganda.
This systematic review and meta-analysis evaluated reported prevalence and diagnostic methods for identifying Candida africana, an opportunistic yeast associated with vaginal and oral candidiasis. A comprehensive literature search yielded 53 studies meeting the inclusion criteria, 2 of which were case studies. The pooled prevalence of C.
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