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A Typical Bezold Abscess With an Atypical Aetiology.
Cureus
December 2024
Department of Otolaryngology, Head and Neck Surgery, General Hospital of Athens "Georgios Gennimatas", Athens, GRC.
Objective: This study aims to present a case of temporal bone (TBP) paraganglioma with an insidious clinical presentation, deviating significantly from the typical hearing loss and pulsatile tinnitus pattern.
Methods: A 70-year-old lady presented to the emergency department with a five-day history of right progressive later cervical swelling extending to the mastoid region and chronic worsening purulent otorrhea. The clinical and radiological findings confirmed the presence of a chronic middle ear process complicated by a Bezold abscess.
Deciphering compromised speech-in-noise intelligibility in older listeners: the role of cochlear synaptopathy.
eNeuro
January 2025
Hearing Technology @ WAVES, Department of Information Technology, Ghent University, Technologiepark 216, 9052 Zwijnaarde, Belgium
Speech intelligibility declines with age and sensorineural hearing damage (SNHL). However, it remains unclear whether cochlear synaptopathy (CS), a recently discovered form of SNHL, significantly contributes to this issue. CS refers to damaged auditory-nerve synapses that innervate the inner hair cells and there is currently no go-to diagnostic test available.
View Article and Find Full Text PDFThe "Outline Sign": Thin Hyperenhancing Perimeter as an MR Imaging Feature of Meningioma. A Useful Tool in the Temporal Bone Region for Differentiating Meningiomas from Schwannomas and Paragangliomas.
AJNR Am J Neuroradiol
January 2025
Department of Radiology (K.L.R, L.V.R., A.F.J.), Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts
Background And Purpose: This study investigates the practicality and utility of the "outline sign," which refers to the thin curvilinear hyperenhancing line that may be seen along the margin of a meningioma on a spin-echo postcontrast T1-weighted image. For cases in which the differential diagnosis may include other tumors, visualization of the outline sign may help to increase the diagnostic confidence for a meningioma. Therefore, in the temporal bone region such as the cerebellopontine angle or jugular foramen, where differential considerations may include a schwannoma or paraganglioma, we additionally investigated whether the outline sign may be observed in these nonmeningioma lesions.
View Article and Find Full Text PDFBreaking the Bone Marrow Barrier: Peripheral Blood as a Gateway to Measurable Residual Disease Detection in Acute Myelogenous Leukemia.
Am J Hematol
January 2025
Division of Oncologic Sciences, Department of Medicine, Oregon Health & Science University, Portland, Oregon, USA.
Acute myeloid leukemia (AML) is a genetically heterogeneous disease with high rates of relapse after initial treatment. Identifying measurable residual disease (MRD) following initial therapy is essential to assess response, predict patient outcomes, and identify those in need of additional intervention. Currently, MRD analysis relies on invasive, serial bone marrow (BM) biopsies, which complicate sample availability and processing time and negatively impact patient experience.
View Article and Find Full Text PDFBilateral squamous cell carcinoma of the temporal bone: A report of two cases and a systematic review of the literature.
J Otol
October 2024
Amsterdam UMC Location Vrije Universiteit Amsterdam, Otorhinolaryngology, De Boelelaan 1117, Amsterdam, the Netherlands.
Objective: two new cases of temporal bone squamous cell carcinoma (TBSCC) with a bilateral occurrence are presented. Furthermore, a review of the literature was performed and the yearly incidence was calculated.
Methods: A systematic review of the literature was conducted using PRISMA guidelines.
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