White rats received rations with varying content of linoleic acid (3.17 and 90 g/kg of food) during 30 days. The control rats that received food with low content of linoleic acid showed a higher content of triglycerides in the liver. Elevation of linoleic acid level in the ration of animals with chronic alcoholic intoxication diminishes the symptoms of alcoholic hepatosis: hepatocyte vacuolization and the content of neutral lipids in them are lowered, serum enzyme (alanine-aminotransferase, gamma-glutamyltransferase) activity decreases as well as the signs of essential fatty acid deficiency disappear.

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