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[Technical standards for performing radiofrequency catheter ablation for atrial fibrillation: a series of consortium standards].
Zhonghua Nei Ke Za Zhi
January 2025
Atrial fibrillation (AF) has emerged as a major global cardiovascular disease in the 21st century. In China, there are greater than 12 million patients with AF, and its incidence continues to rise. AF affects patients' quality of life and significantly increases the risks of mortality, stroke, heart failure, cognitive impairment, and dementia.
View Article and Find Full Text PDFThe value of diabetes technology enabled coaching (DTEC) to support remission evaluation of medical interventions in T2D: Patient and health coach perspectives.
PLOS Digit Health
January 2025
School of Nursing, McMaster University, Hamilton, Ontario, Canada.
The multicomponent Remission Evaluation of Medical Interventions in T2D (REMIT) program has shown reduction of hazard of diabetes relapse by 34-43%, but could benefit from improved ability to scale, spread, and sustain it. This study explored, at the conceptualization phase, patient and health coach perspectives on the acceptability, adoption, feasibility, and appropriateness of a digital REMIT adaptation (diabetes technology enabled coaching (DTEC)). Twelve semi-structured interviews were conducted with patients (n = 6) and health coaches (n = 6) to explore their experiences with the REMIT study, opportunities for virtualisation, and a cognitive walkthrough of solution concepts.
View Article and Find Full Text PDFBiomarkers.
Alzheimers Dement
December 2024
Neurocognitive Unit, Division of Neurology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Background: Alzheimer's disease(AD) raises global concern with its impact on daily living. Anti-amyloid monoclonal antibodies (mAb) serving as specific treatments used in mild cognitive impairment(MCI) and mild dementia due to AD. Severe cerebral small vessel disease(SVD) lesions such as microbleeds and white matter hyperintensities are listed as exclusions according to the recommendation for mAb treatment.
View Article and Find Full Text PDFBiomarkers.
Alzheimers Dement
December 2024
Clinical Research Center, Department of Medical Research, Yangon, Myanmar.
Background: Diabetes mellitus increases the risk of cognitive decline and neuronal degeneration. In diabetes, persistently elevated blood sugar levels cause not only the generation of reactive oxygen species (ROS), but also systemic inflammation (1). This raises an intriguing question: do patients with controlled or uncontrolled diabetes exhibit similar levels of oxidative stress and systemic inflammation as reliable predictors of peripheral neuropathy and cognitive decline?
Method: In 2019, 150 participants with diabetes mellitus who had been diagnosed for more than 5 years were voluntarily enrolled.
Background: Underrepresented racial and ethnic groups have higher rates of clinical dementia symptoms and are given clinical diagnoses of Alzheimer's disease without confirmatory AD biomarkers.
Method: We compared amyloid PET positivity in cohort of all rural and suburban Southeastern participants from a single clinical practice who met appropriate-use criteria for amyloid PET imaging between January 2020-December 2024. We used a paired nominal date test McNemar test to compare amyloid PET positivity proportions between matched racial and ethnic groups and multivariable logistic regression to assess the odds of having a positive amyloid PET scan.
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