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Discovery of small molecules against porcine reproductive and respiratory syndrome virus replication by targeting NendoU activity.
J Virol
December 2024
Department of Animal Science, Institute for Systems Genomics, University of Connecticut, Storrs, Connecticut, USA.
Unlabelled: Porcine reproductive and respiratory syndrome (PRRS) remains a major threat to animal health and causes substantial economic losses worldwide. The nonstructural protein 11 (NSP11) of the causative agent, PRRS virus (PRRSV), contains a highly conserved nidoviral uridylate-specific endoribonuclease (NendoU) domain essential for viral replication and immune evasion. Targeting NSP11 offers a novel approach to antiviral intervention.
View Article and Find Full Text PDFInterfacial Engineering with One-Dimensional Lepidocrocite TiO-Based Nanofilaments for High-Performance Perovskite Solar Cells.
ACS Omega
December 2024
Department of Material Science and Engineering, Drexel University, Philadelphia 19104, Pennsylvania, United States.
The optimization of nonradiative recombination losses through interface engineering is key to the development of efficient, stable, and hysteresis-free perovskite solar cells (PSCs). In this study, for the first time in solar cell technology, we present a novel approach to interface modification by employing one-dimensional lepidocrocite (henceforth referred to as 1DL) TiO-based nanofilaments, NFs, between the mesoporous TiO (mp TiO) and halide perovskite film in PSCs to improve both the efficiency and stability of the devices. The 1DLs can be easily produced on the kilogram scale starting with cheap and earth-abundant precursor powders, such as TiC, TiN, TiB, etc.
View Article and Find Full Text PDFNear-infrared germanium PIN-photodiodes with >1A/W responsivity.
Light Sci Appl
January 2025
Aalto University, Department of Electronics and Nanoengineering, Espoo, Finland.
Even though efficient near-infrared (NIR) detection is critical for numerous applications, state-of-the-art NIR detectors either suffer from limited capability of detecting incoming photons, i.e., have poor spectral responsivity, or are made of expensive group III-V non-CMOS compatible materials.
View Article and Find Full Text PDFBiocontrol mechanisms of antagonistic yeasts on postharvest fruits and vegetables and the approaches to enhance the biocontrol potential of antagonistic yeasts.
Int J Food Microbiol
December 2024
National Key Laboratory of Tropical Crop Breeding, School of Tropical Agriculture and Foresty, Hainan University, Haikou 570228, Hainan, China. Electronic address:
During storage and transportation, fruits and vegetables are susceptible to various pathogens, leading to quality degradation and significant economic losses. Currently, chemical pesticides are primarily used for control; however, their overuse poses serious threats to human health and causes environmental pollution. Biocontrol, known for its environmentally friendly characteristics, has been extensively studied.
View Article and Find Full Text PDFPrevalence of Cystic Echinococcosis in Sheep and Goats of Ethiopia: A Systematic Review and Meta-Analysis.
Vet Med Sci
January 2025
Department of Veterinary Sciences, Salale University, Fiche, Ethiopia.
Cystic echinococcosis (CE) is a cestode infection of significant public health and economic importance. A systematic review and meta-analysis was performed to estimate the pooled prevalence of small ruminant CE and associated risk factors in Ethiopia. The published literature written in English from 01 January 2000 to 30 December 2019 was searched from electronic databases and eligible reports that fulfilled inclusion and exclusion criteria.
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