Mono-octanoin (Mo) is the drug of choice in the topical litholytic treatment of residual gallstones following cholecystectomy. Although this drug does not produce significant side effects, it requires a lengthy period of treatment (15-20 days). The purpose of this study was to verify the in vitro efficacy of the mixture Mo + 10% H2O vs pure Mo in human cholesterol stones. The findings indicate that this mixture can reduce dissolution time by 15.8% and increase the dissolution rate by 27.9% vs pure Mo. A further significant reduction (p = 0.0001) in dissolution times can be obtained by constant exchange of the solvent at the surface of the stone (stirring).
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Rapid fabrication and dissolution of pressed Ni/Mg matrix targets for Co production.
EJNMMI Radiopharm Chem
January 2025
Department of Nuclear Medicine and Medical Physics, Karolinska University Hospital, Stockholm, 171 76, Sweden.
Background: Beyond the use of conventional short-lived PET radionuclides, there is a growing interest in tracking larger biomolecules and exploring radiotheranostic applications. One promising option for imaging medium-sized molecules and peptides is ⁵⁵Co (T₁/₂ = 17.5 h, β⁺ = 76%), which enables imaging of new and already established tracers with blood circulation of several hours.
View Article and Find Full Text PDFPositionality statements: Intersectional considerations for rehabilitation psychology.
Rehabil Psychol
February 2025
Department of Psychiatry and Behavioral Health, Ohio State University Wexner Medical Center.
Introduction: Positionality statements accompanying peer-reviewed publications are increasingly being implemented in academic journals across many disciplines, including psychology. These statements serve as transparent, public acknowledgments of the authors' identities, which can offer valuable insight into the authors' work in the context of their lived experiences and potential biases. However, journal editors and associated staff risk harm by uniformly adopting a policy on positionality statements without consideration of the unintended consequences of implementing such practices.
View Article and Find Full Text PDFSynthesis and characteristics of water-based, rosin-modified, polymerized oil based on dehydrated castor oil acid and zinc resinate.
RSC Adv
January 2025
High-Tech Research and Development Center, Kim Il Sung University Pyongyang Democratic People's Republic of Korea
In this study, we synthesized a water-based, rosin-modified, polymerized oil (WRPO) an addition and polymerization reaction of dehydrated castor oil (DCO), rosin acid (RA), zinc resinate (ZR) and dehydrated castor oil acid (DCOA). Addition and polymerization reactions at 240 °C, followed by neutralization with ammonia, dissolution into butyl alcohol and subsequent dilution with water, were performed at varying DCOA contents of 10%, 20%, 30%, 35% and 40%. WRPO was mixed with butoxymethylmelamine (BMM), a curing agent, at a weight ratio of 80 : 20, and then cured for 2 hours at 130 °C.
View Article and Find Full Text PDFStatus analysis of quality control of administered infusion solution with cytotoxic drugs.
Oncol Rev
January 2025
Department of Pharmacy, Tianjin First Central Hospital, Nankai University, Tianjin, China.
The administered infusion solution is a sterile preparation that can be used directly for intravenous infusion in patients by mixing one or more intravenous drugs using aseptic operation technology. The pharmacy intravenous admixture service (PIVAS) center is a professional technical service department in hospitals, where the majority of inpatient-administered infusion solutions are prepared. During the processes of dissolution, dilution, preparation, storage, and use of intravenous drugs, the quality control of the administered infusion solution can be affected by various factors.
View Article and Find Full Text PDFAssessment on surface integrity in electrochemical grinding of AISI 304.
Heliyon
January 2025
Advanced Technologies of Machine Tools (ATMT) Lab, Faculty of Mechanical Engineering, Tarbiat Modares University, Tehran, Iran.
Electrochemical grinding (ECG) offers advantages such as burr-free and stress-free material removal. Despite its proven potential, limited research has addressed the comprehensive effects of key process parameters on the surface integrity of AISI 304 stainless steel, particularly for applications requiring high-quality finishes, such as medical components. This study bridges this gap by systematically investigating the influence of ECG key parameters including voltage, rotational speed, and electrolyte concentration on main surface integrity parameters including current density, surface roughness, microhardness, and surface texture.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!