Etiopathogenesis of orofacial clefting revisited.

J Oral Maxillofac Pathol

Department of Oral Pathology, Yenepoya Dental College, Mangalore, Karnataka, India.

Published: May 2012

The cleft anomaly may be more ancient than the man himself. It is one of the most common developmental malformations reported in the literature. There are number of intriguing theories regarding its etiopathogenesis, each of which has some evidence in its favor. This review highlights all the genetic and environmental etiologic factors and focuses on its pathogenesis.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424939PMC
http://dx.doi.org/10.4103/0973-029X.99074DOI Listing

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