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Ebstein's anomaly with coarctation of the aorta and a bicuspid aortic valve: a case report of a rare association with unique prenatal findings.
Cardiol Young
October 2024
Division of Pediatric Cardiology, Osaka City General Hospital, Osaka, Japan.
Article Synopsis
- - Ebstein's anomaly is an uncommon heart condition that rarely occurs with coarctation of the aorta, despite patients often having a small left ventricle.
- - The case presented involves a unique combination of Ebstein's anomaly, coarctation of the aorta, and a bicuspid aortic valve.
- - The study compares fetal echocardiographic data from this case to five previous similar cases to investigate the relationship between left ventricular volume, severity of Ebstein's anomaly, and the presence of left heart obstruction.
Study on ultrasound diagnosis and pathological anatomy of fetal complex congenital heart disease in the first trimester.
J Clin Ultrasound
September 2024
Obstetrics Department, Guangxi Maternity & Child Healthcare Hospital, Nanning, China.
Purpose: To assess the feasibility of using the stereo-microscope to identify the pathological anatomy of the congenital heart diseases in the first trimester.
Methods: Fifteen fetuses of 8-12 weeks aborted due to prevent miscarriage failure and 42 fetuses of 11-14 weeks with congenital heart diseases were included in the study, we dissected their hearts through a stereo-microscope, then compared with the prenatal ultrasonographic diagnosis.
Results: Using stereomicroscopy, the positive view of the heart and the great arteries, the long axis view of the aortic arch, the inflow tract view of the bottom heart, the semilunar valve view of the bottom heart, and the transverse section of the ventricle were showed contented and obtained satisfactory images, but the structure of atrioventricular valve and venous system had a lower rate of display.
Diagnosis of Congenital Heart Disease in Adulthood: How Often, How Relevant?
Am J Cardiol
November 2024
University hospital La Paz, Madrid, Spain; La Paz Hospital Institute for Health Research, (IdiPAZ), Madrid, Spain.
Congenital heart disease (CHD) is typically detected during fetal life, infancy, or early childhood. However, there is no published data regarding the proportion of congenital heart defects that are diagnosed in adulthood or the impact of these defects. Retrospective analyses of all consecutive patients (n = 1,010) referred to an adult CHD unit between 2018 and 2023.
View Article and Find Full Text PDFObstetric Outcomes in Women on Lithium: A Systematic Review and Meta-Analysis.
J Clin Med
August 2024
Department of Psychiatry, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, L.Go Agostino Gemelli 8, 00168 Rome, Italy.
Article Synopsis
- Lithium during pregnancy has been linked to potential foetal malformations, but treatment for maternal psychiatric conditions is often deemed more critical by clinicians.
- A systematic review analyzed 28 studies, with meta-analysis including data from 1402 newborns and 2595 women, revealing increased risks of cardiac malformations, preterm birth, and being large for gestational age among those taking lithium.
- Women with bipolar disorder should consider stopping lithium before pregnancy if stable, but if they continue during pregnancy, they should have close monitoring to manage potential risks.
Prenatal Cardiac Ultrasound Markers of Outcomes in Ebstein's Anomaly: An International Multicenter Case Series.
Pediatr Cardiol
June 2024
Department of Obstetrics, Paulista School of Medicine, Federal University of São Paulo (EPM-UNIFESP), São Paulo-SP, Brazil, Rua Belchior de Azevedo, 156 Apto. 111 Torre Vitória, 05089-030.
Article Synopsis
- - The study analyzed prenatal cardiac ultrasound markers in 35 fetuses diagnosed with Ebstein's anomaly (EA) across three countries, focusing on perinatal mortality and outcomes through retrospective data analysis.
- - Out of 29 fetuses eligible for the study, 53.1% were born alive, while others faced a mix of stillbirths, neonatal deaths, and fetal deaths; among the surviving patients, most underwent successful biventricular repair surgery postnatally.
- - The findings indicated that severe tricuspid regurgitation and pulmonary atresia were common, with significant cardiomegaly noted in many cases, while a few fetuses exhibited abnormal karyotypes linked to poorer outcomes.
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