The in vitro activity of LY 264826, a new glycopeptide antibiotic, was compared with that of vancomycin against 100 strains each of methicillin-resistant Staphylococcus aureus and Clostridium difficile. LY 264826 was more active, by weight, than vancomycin against the isolates tested. The human serum protein binding of LY 264826 was 15.3% (range, 9.8 to 21.8%).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC171979PMC
http://dx.doi.org/10.1128/AAC.34.10.2007DOI Listing

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