Purpose: To determine if any single abnormal semen parameter is associated with low hypoosmotic swelling (HOS) test scores.
Methods: A retrospective review evaluating males with single sperm defects of sperm concentration, % progressive motility, morphology using strict criteria, and antisperm antibodies. The percentage of these males with HOS test scores < 50% was then determined.
Results: By far the abnormal semen parameter most associated with a subnormal HOS test was poor motility.
Conclusions: Though we believe that the simple inexpensive HOS test should be performed routinely when performing semen analysis, it is especially important to evaluate in males with poor motility since simple intrauterine insemination will not allow pregnancies.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Sex-Based Differences in the Arthroscopic Treatment of Femoroacetabular Impingement Syndrome: 10-Year Outcomes With a Nested Propensity-Matched Comparison.
Am J Sports Med
January 2025
American Hip Institute Research Foundation, Des Plaines, Illinois, USA.
Background: Sex has been associated with different pathologic characteristics in painful hips undergoing hip arthroscopic surgery.
Purpose: To compare minimum 10-year patient-reported outcomes (PROs) and survivorship in patients who underwent primary hip arthroscopic surgery for femoroacetabular impingement syndrome and labral tears according to sex.
Study Design: Cohort study; Level of evidence, 3.
Association of Preoperative Walking Speed With 1-Year Outcomes After Hip Arthroscopy for Femoroacetabular Impingement Syndrome.
Sports Health
January 2025
Section of Young Adult Hip Surgery, Division of Sports Medicine, Department of Orthopaedic Surgery, Rush Medical College of Rush University, Rush University Medical Center, Chicago, Illinois.
Background: Previous studies have identified demographic, radiographic, and intraoperative predictors of outcomes after hip arthroscopy for femoroacetabular impingement syndrome, yet few studies have identified whether preoperative gait metrics can predict outcomes.
Hypothesis: Increased preoperative step count, walking speed, step length, and gait symmetry will be associated with better outcomes after surgery.
Study Design: Retrospective cohort study.
Boronic Acid-Containing 3- pyrazolo[4,3-]quinoline Compounds as Dual CLK/ROCK Inhibitors with Anticancer Properties.
Pharmaceuticals (Basel)
December 2024
Department of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, IN 47907, USA.
The protein kinases CLK and ROCK play key roles in cell growth and migration, respectively, and are potential anticancer targets. ROCK inhibitors have been approved by the FDA for various diseases and CLK inhibitors are currently being trialed in the clinic as anticancer agents. Compounds with polypharmacology are desired, especially in oncology, due to the potential for high efficacy as well as addressing resistance issues.
View Article and Find Full Text PDFApplication of additive manufacturing TaBw01 porous tantalum rod in ARCO stage II osteonecrosis of the femoral head.
J Orthop Surg Res
December 2024
Center for Joint Surgery, Southwest Hospital, Army Medical University, Gaotanyan Street, Shapingba District, Chongqing, 400038, China.
Purpose: This study aims to investigate the suitable surgical strategies for applying TaBw01 porous tantalum rod across different stages of osteonecrosis of the femoral head (ONFH).
Methods: TaBw01 tantalum rods were fabricated using type FTaY-1 tantalum powder via the foam impregnation-sintering method. Mechanical testing with the Instron 8801 universal testing machine and finite element analysis (FEA) assessed single tantalum rod implantation and impaction bone grafting combined with rod implantation.
Sphingolipids modulate redox signalling during human sperm capacitation.
Hum Reprod
December 2024
Experimental Medicine Division, Department of Medicine, McGill University, Montréal, QC, Canada.
Study Question: What role do sphingolipids have in mediating human sperm capacitation?
Summary Answer: Sphingosine 1-phosphate (S1P) mediates the acquisition of fertilizing competency in human spermatozoa by engaging with its Gi-coupled receptor S1PR1 and promoting production of reactive oxygen species such as nitric oxide and superoxide anion.
What Is Known Already: Bioactive sphingolipids, such as S1P, are fundamental for regulating numerous physiological domains and processes, such as cell membranes and signalling, cell death and proliferation, cell migration and invasiveness, inflammation, and central nervous system development.
Study Design, Size, Duration: Semen samples were obtained from a cohort of 10 healthy non-smoking volunteers (18-30 years old) to investigate the role of S1P in sperm.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!