The paper analyses the characteristics of mathematical methods for detecting the biorhythms currently used for the chronodiagnosis and chronotherapy of cardiovascular diseases. Emphasis is laid on the assessment of the resolving power of algorithms and programs applied to the detection of circadian biological rhythms. The paper also discusses whether chronodiagnosis and chronotherapy of cardiovascular diseases are admissible by clinically available mathematical methods for detecting circadian rhythms. In addition, it deals with theoretical conditions required for accurate detection of varying frequency biological rhythms from length-limited data arrays and proposes a mathematical method suitable to a problem to detect biological rhythms with periods unknown in advance.

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