Objective: To study legal cases against IVF facilities pertaining to preimplantation genetic diagnosis (PGD) misdiagnosis.
Design: Systematic case law review.
Setting: University medical center using US legal databases.
Patient(s): The IVF recipients using PGD services.
Intervention(s): Lawsuits pertaining to PGD against IVF facilities.
Main Outcome Measure(s): Lawsuits, court rulings, damage awards, and settlements pertaining to PGD after the birth of a child with a genetic defect.
Result(s): Causes of action pertaining to PGD arise from negligence in performing the procedure as well as failure to properly inform patients of key information, such as inherent errors associated with the PGD process, a facility's minimal experience in performing PGD, and the option of obtaining PGD. Courts have sympathized with the financial burden involved in caring for children with disabilities. Monetary damage awards are based on the costs of caring for children with debilitating defects, including lifetime medical and custodial care.
Conclusion(s): Facilities offering PGD services expose themselves to a new realm of liability in which damage awards can easily exceed the limits of a facility's insurance policy. Competent laboratory personnel and proper informed consent--with particular care to inform patients of the inherent inaccuracies of PGD--are crucial in helping deter liability.
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http://dx.doi.org/10.1016/j.fertnstert.2012.07.1100 | DOI Listing |
Front Immunol
February 2024
Department of Cardiothoracic Surgery, Mayo Clinic Arizona, Phoenix, AZ, United States.
Primary Graft Dysfunction (PGD) is a major cause of both short-term and long-term morbidity and mortality following lung transplantation. Various donor, recipient, and technical risk factors have been previously identified as being associated with the development of PGD. Here, we present a comprehensive review of the current literature as it pertains to PGD following lung transplantation, as well as discussing current strategies to mitigate PGD and future directions.
View Article and Find Full Text PDFJ Biomed Mater Res B Appl Biomater
April 2023
Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, Georgia, USA.
Biodegradable shape memory polymers provide unique regenerative medicine approaches in minimally invasive surgeries. Once heated, thermally responsive shape memory polymer devices can be compressed, programmed to fit within a small profile, delivered in the cold programmed state, and expanded when heated to body temperature. We have previously developed a biodegradable shape memory elastomer (SME), poly(glycerol dodecanedioate) (PGD), with transition temperatures near 37°C exhibiting nonlinear elastic properties like numerous soft tissues.
View Article and Find Full Text PDFLife (Basel)
January 2022
Maxillofacial Surgery Operative Unit, Department of Medical, Surgical and Experimental Sciences, University of Sassari, 07100 Sassari, Italy.
(1) Background: Persistent olfactory (POD) and gustatory (PGD) dysfunctions are one of the most frequent symptoms of long-Coronavirus Disease 2019 but their effect on the quality of life (QoL) of patients is still largely unexplored. (2) Methods: An online survey was administered to individuals who reported to have had SARS-CoV-2 infection at least 6 months prior with persisting COVID-19 symptoms (using the COVID symptom index), including ratings of POD and PGD, and their physical (PCS) and mental (MCS) components of quality of life were assessed using the standardized short form 12 questionnaire (SF-12). (3) Results: Responses from 431 unique individuals were included in the analyses.
View Article and Find Full Text PDFPak J Med Sci
January 2019
Prof. Dr. Iram Manzoor, FCPS. Community Medicine MCPS Medical Education, Akther Saeed Medical and Dental College, Lahore, Pakistan.
Background And Objectives: During the past few decades, females had been making conscious decision to have antenatal checkup from skilled health care provider due to improved education which had played a vital role to enhance their awareness regarding the importance of this comprehensive health service. The objective was to find out the perception of females of child bearing age about the importance of antenatal care during their last pregnancy, living in a suburban community of Kot-Lakhodare Lahore.
Methods: Females of reproductive age (15-49 years) living in Kot-Lakhodare were enrolled.
Fertil Steril
January 2018
IVF Unit, Hadassah Hebrew University Medical Center, Jerusalem, Israel.
Deleterious mutations in BRCA1 or BRCA2 genes have long been recognized as independent risk factors, mostly for breast and ovarian cancer. Numerous studies have evaluated the molecular processes involving these genes, the pathophysiology of BRCAness, follow up options and modes of prophylaxis. The fertility of BRCA carriers, however, has not been widely investigated.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!