Acute upper limb ischaemia (AULI) can be managed surgically, via interventional radiology, and conservatively, but no real guidelines exist for when a conservative approach is appropriate. A systematic review of the literature is presented of the surgical, radiological and conservative management of AULI. A search was performed using the electronic databases Medline and Embase. Interventions and outcomes for each study were recorded. The consensus from the literature review was that operative management (embolectomy) is the most commonly used and best first-line treatment for AULI. No studies that used conservative anticoagulation management as a primary therapy, this mainly being reserved for patients deemed unfit for interventional treatment, appear in the literature. The consensus from the literature is that operative management is the most commonly used and best treatment. However, bias toward using operative management for the fittest patients appears in the literature. It is also possible that conservative management is underreported.
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http://dx.doi.org/10.1016/j.jvn.2012.03.002 | DOI Listing |
Sci Rep
December 2024
Medical Genomics Research Department, King Abdullah International Medical Research Center, King Saud bin Abdulaziz University for Health Sciences, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia.
In order to plan and facilitate the culture of personalized / precision medicine in medical practices within any healthcare institution, it is requisite for healthcare professionals like clinicians to have a clear understanding and approach towards the practices of personalized genetic testing. This nationwide cross-sectional study aimed to measure the perceptions and knowledge of clinicians towards personalized genetic testing and assess their current practices of personalized genetic testing in clinical settings through an online self-administered questionnaire in Saudi Arabia. The results of the study revealed that almost two-fifths of participants were responsible for ordering genetic tests directly (39.
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December 2024
Department of Pediatric Surgery, West China Hospital, Sichuan University, Chengdu, China.
This study aimed to investigate the safety and effect of omitting chest tubes after thoracoscopic lobectomy in children with congenital lung malformation. A multicenter retrospective study was performed with 632 thoracoscopic lobectomy CLM patients in four hospitals between 2014.1 and 2023.
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December 2024
Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA.
The unintended consequences of polypharmacy pose significant risks to older adults. The complexities of managing numerous medications from multiple prescribers demand a comprehensive approach to mitigate harms. Pharmacist-led clinics have been shown to improve outcomes in patients with diabetes and hypertension.
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December 2024
Department of Orthopedic Surgery, Arthroscopy and Joint Research Institute, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
The humeral head is the second most common anatomical site of osteonecrosis after the femoral head. Studies have reported satisfactory clinical outcomes after shoulder arthroplasty to treat osteonecrosis of the humeral head (ONHH). However, there are concerns regarding implant longevity in relatively young patients.
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December 2024
Institute of Soil and Water Conservation, Northwest A&F University, Yangling, 712100, Shaanxi, China.
Reservoir-operation optimisation is a crucial aspect of water-resource development and sustainable water process management. This study addresses bi-objective optimisation problems by proposing a novel crossover evolution operator, known as the hybrid simulated binary and improved arithmetic crossover (SBAX) operator, based on the simulated binary cross (SBX) and arithmetic crossover operators, and applies it to the Non-dominated Sorting Genetic Algorithms-II (NSGA-II) algorithm to improve the algorithm. In particular, the arithmetic crossover operator can obtain an optimal solution more precisely within the solution space, whereas the SBX operator can explore a broader range of potential high-quality solutions.
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