Congenital granular cell lesion of the newborn, also known as congenital epulis, is a rare benign oral cavity tumor presenting at birth. Usually, it appears as a solitary mass arising in the mouth and originates from the anterior alveolar ridge. The objective of the present article is to report a case of congenital granular cell lesion in an 8-day-old female newborn. The patient presented four intraoral pedunculated lesions. Diagnosis, treatment, microscopic and immunohistochemical characteristics are also discussed.
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http://dx.doi.org/10.17796/jcpd.36.1.y1x9526472206504 | DOI Listing |
Neurol India
November 2024
Department of Pathology, All India Institute of Medical Sciences, New Delhi, India.
Sporadic late-onset nemaline rod myopathy is a rare, acquired, sub-acute, adult-onset myopathy characterized by proximal muscle weakness and nemaline rods in the myofibers. In contrast to its congenital form, the prevalence in adult population is comparatively rare. Herein, we report a case of 60-year-old male who presented with insidious onset proximal muscle weakness with myopathic pattern on electromyography.
View Article and Find Full Text PDFHum Reprod
December 2024
Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Study Question: What are the roles of maternal preconception diabetes and related periconceptional hyperglycemia on the risk of major congenital malformations (MCMs) in offspring?
Summary Answer: Maternal periconceptional glycated hemoglobin (HbA1c) levels over 5.6% were associated with an increased risk of congenital heart defects (CHD) in the offspring, and maternal preconception diabetes was associated with an increased risk of CHD, including when HbA1c levels were within euglycemic ranges.
What Is Known Already: Maternal preconception diabetes has been linked with MCMs in the offspring.
Cardiol Young
October 2024
Congenital Heart Center, Atrium Health Levine Children's Hospital, Charlotte, NC, USA.
Am J Obstet Gynecol MFM
October 2024
Department of Obstetrics and Gynecology, Macon and Joan Brock Virginia Health Sciences at Old Dominion University, Norfolk, VA (Atwani, Saade, Kawakita).
Int J Surg Case Rep
September 2024
Department of maxillofacial surgery, College of Medicine and Health Sciences, University of Gondar, Maraki 196, Gondar, Ethiopia.
Introduction: Congenital epulis, also known as Neumann's tumor, is an uncommon benign tumor of the oral mucosa that occurs in newborns. It is a rare condition, with fewer than 250 reported cases worldwide. The exact cause or underlying mechanism of this tumor is still not well understood.
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