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Rates of fatty acid oxidations by P450 compound I are pH dependent. | LitMetric

Rates of fatty acid oxidations by P450 compound I are pH dependent.

Chembiochem

Department of Chemistry, University of Illinois at Chicago, 845 W. Taylor St., Chicago, IL 60607, USA.

Published: September 2012

The rates of oxidation of fatty acids by CYP119 compound I were dependent on the pH of the medium. The plot shows log k values for reactions of acids as a function of pH, where the slopes indicate mixed third-order and fourth-order dependence on base concentration. For palmitic acid, the rate increased 50-fold over the pH range 6.8-7.3.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477493PMC
http://dx.doi.org/10.1002/cbic.201200387DOI Listing

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