Objective: To investigate the in vitro efficacy of commercially available topical otic preparations ("ear cleaners") against Pseudomonas spp. isolated from canine ear infections.
Methods: Between January and May 2011, 50 isolates that were morphologically and phenotypically confirmed as Pseudomonas spp. were isolated from 48 dogs that had been identified with clinical signs of otitis externa and media at a referral dermatology clinic in the north west of the UK. The in vitro efficacy of eight different topical preparations against these isolates was investigated using an in-agar inhibition test.
Results: Of the eight preparations tested, three showed consistently good in vitro activity against Pseudomonas spp., while a further three were consistently ineffective. For the remaining two -preparations, in vitro efficacy was variable and inconsistent.
Clinical Significance: Topical treatment with ear cleaners is considered to be a valuable adjunct in the treatment of canine otitis that involves multi-antimicrobial-resistant organisms such as Pseudomonas spp. Where treatment with antimicrobials is not an option, the use of these preparations, as a sole form of therapy, may be effective in some cases. As a comparison with other similar studies looking at the activity of ear cleaners against bacterial isolates from otitis, this study uses isolates from 50 ears from 48 dogs providing a significant number of isolates for analysis.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/j.1748-5827.2012.01262.x | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Increasing microplastics pollution: An emerging vector for potentially pathogenic bacteria in the environment.
Water Res
January 2025
Leibniz-Institute of Freshwater Ecology and Inland Fisheries (IGB), Neuglobsow 16775, Germany; Institute of Biochemistry and Biology, Potsdam University, Potsdam 14469, Germany.
Microplastics (MP), plastic particles <5 mm, are of global concern due to their worldwide distribution and potential repercussions on ecosystems and human well-being. In this study, MP were collected from the urbanized Susurluk basin in Türkiye to evaluate their vector function for bacterial biofilms, both in the wet and dry seasons. Bacterial biofilms were predominantly found on polyethylene (PE), polypropylene (PP), and polystyrene (PS), which constitute the most common MP types in the region.
View Article and Find Full Text PDFThe economic burden of post-endoscopic retrograde cholangiopancreatography (ERCP) procedure infections in Italy.
Glob Reg Health Technol Assess
December 2024
Department of Hospital Pharmacy, Città della Salute e della Scienza di Torino, Turin - Italy.
Introduction: The infections of multidrug-resistant organisms (MDROs) associated with duodenoscopes during endoscopic retrograde cholangiopancreatography (ERCP) procedure have become a significant cause for concern, especially in fragile patients. While the clinical impacts of these infections are well-documented, their economic implications remain underexplored. This study assesses the incidence and economic burden of post-ERCP infections in Italy using an administrative database.
View Article and Find Full Text PDFShelf-life enhancement of silver carp fillets using psyllium gum/sodium-alginate coatings incorporated with essential oil and CuO nanoparticles.
Food Sci Technol Int
January 2025
Department of Food Hygiene, Science and Research Branch, Islamic Azad University, Tehran, Iran.
In the present study, the effects of psyllium gum/sodium-alginate (PG/SA) coatings incorporated with essential oil (HEO) and copper oxide nanoparticles (CuO NPs) on various properties of silver carp fillets were investigated and monitored over 15 days of chilled storage condition (4 °C ± 1). The control sample (uncoated), PG/SA with 3% CuO NPs, PG/SA with 1% HEO, and PG/SA with 3% CuO NPs and 1% HEO (PG/SA-HC) were examined through chemical, microbial, and sensory analysis. The results revealed that the PG/SA-HC sample after 15 days of refrigeration demonstrated a significantly lower value than the others for total viable counts (8.
View Article and Find Full Text PDFsp. nov., a novel endophytic bacterium with plant growth-promoting potential, isolated from root nodules of in Northwestern Algeria.
Int J Syst Evol Microbiol
January 2025
Dpartement de Biotechnologie, Laboratoire des Productions, Valorisations Vgtales et Microbiennes (LP2VM), Facult des Sciences de la Nature et de la Vie, B.P. 1505, El-Mnaour, Universit des Sciences et de la Technologie dOran Mohamed Boudiaf USTO-MB, Oran 31000, Algeria.
A thorough polyphasic taxonomic study, integrating genome-based taxonomic approaches, was carried out to characterize the RB5 strain isolated from root nodules of growing on the coastal dunes of Bousfer Beach (Oran, Algeria). The 16S rRNA gene sequence analysis revealed that strain RB5 had the highest similarity to LMG27940 (98.94%) and IzPS32d (98.
View Article and Find Full Text PDFComplex management of GS (Good's syndrome) with persistent COVID-19 infection and polymicrobial infections: A case report.
Heliyon
January 2025
Zhongshan Hospital (Xiamen), Fudan University, Xiamen City, 361015, China.
This case report highlights the diagnostic and therapeutic complexities faced by a 56-year-old female with Good's syndrome (GS), who presented with persistent Coronavirus Disease 2019 (COVID-19) infection alongside spp, , and co-infection, which collectively contributed to severe pulmonary involvement. The report further emphasizes a multifaceted treatment approach, incorporating antivirals, antifungals, antimicrobials, immunoglobulins, and antifibrotic therapy, which ultimately led to an improvement in the patient's condition. It underscored the intricate challenges of managing immunocompromised patients with multiple concurrent infections.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!