Dynamic concurrent partnership networks incorporating demography.

Theor Popul Biol

Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, Universiteitsweg 100, 3584 CG Utrecht, The Netherlands.

Published: November 2012

We introduce a population model that incorporates From a mathematical point of view we deal with continuous-time Markov chains at the individual level, with the interaction between individuals captured by a global variable describing opportunities for new partnerships. We show that for large time a stationary distribution is attained and we deduce various statistical features of that distribution, with particular attention for concurrency, i.e. the overlap in time of multiple partnerships of one and the same individual. Our ultimate motivation is to model the spread of sexually transmitted infections in the population, for which the present paper serves as a prelude.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tpb.2012.07.001DOI Listing

Publication Analysis

Top Keywords

dynamic concurrent
4
concurrent partnership
4
partnership networks
4
networks incorporating
4
incorporating demography
4
demography introduce
4
introduce population
4
population model
4
model incorporates
4
incorporates mathematical
4

Similar Publications

Astragali Radix-Notoginseng Radix et Rhizoma medicine pair prevents cardiac remodeling by improving mitochondrial dynamic balance.

Chin J Nat Med

January 2025

Jiangsu Key Laboratory of TCM Evaluation and Translational Research, Research Center for Traceability and Standardization of TCMs, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 211198, China. Electronic address:

Astragali Radix (AR) and Notoginseng Radix et Rhizoma (NR) are frequently employed in cardiovascular disease treatment. However, the efficacy of the AR-NR medicine pair (AN) in improving cardiac remodeling and its underlying mechanism remains unclear. This study aimed to evaluate AN's cardioprotective effect and potential mechanism on cardiac remodeling using transverse aortic constriction (TAC) in mice and angiotensin II (Ang II)-induced neonatal rat cardiomyocytes (NRCMs) and fibroblasts in vitro.

View Article and Find Full Text PDF

Establishing a Pan-European, multi-disciplinary taphonomic research Infrastructure: The 'UK-Netherlands decomposition experimental research (UNDER) Group'.

Sci Justice

January 2025

Department of Forensic Science, School of Life Science, Atlantic Technology University (ATU), Sligo, F91 YW50, Ireland; Department of Forensic and Crime Science, Staffordshire University, College Road, Stoke-on-Trent, Staffordshire ST4 2DE, UK.

This study unveils the establishment of the United Kingdom-Netherlands Decomposition Experimental Research (UNDER) working group, marking a pioneering initiative in practical Forensic Taphonomy within the UK. Our primary objective was to craft a cohesive multidisciplinary framework, designed to ethically orchestrate, execute, and assess human decomposition. Concurrently, we aimed to amass data through human burials, fostering collaboration among diverse forensic experts across Europe.

View Article and Find Full Text PDF

Comprehensive analysis of the transcriptome-wide m6A Methylome in sheep testicular development.

Genomics

January 2025

Key Laboratory of Animal Genetics and Breeding on the Tibetan Plateau, Ministry of Agriculture and Rural Affairs, Lanzhou Institute of Husbandry and Pharmaceutical Sciences, Chinese Academy of Agricultural Sciences, Lanzhou 730050, China; Sheep Breeding Engineering Technology Research Center of Chinese Academy of Agricultural Sciences, Lanzhou 730050, China. Electronic address:

N6-methyladenosine (m6A) modification of RNA is a critical post-transcriptional modification, that dynamically contributes to testicular development and spermatogenesis. Nevertheless, the investigation into the role of m6A in testicular development of sheep remains insufficient. Herein, we conducted a comprehensive analysis of the m6A transcriptome landscape in the testes of F1 hybrid Southdown × Hu sheep across M0 (0 months old, newborn), M3 (3 months old, sexually immature), M6 (6 months old, sexually mature), and Y1 (1 years old, adult).

View Article and Find Full Text PDF

Objective: The complex mix of factors, including hemodynamic forces and wall remodeling mechanisms, that drive intracranial aneurysm growth is unclear. This study focuses on the specific regions within aneurysm walls where growth occurs and their relationship to the prevalent hemodynamic conditions to reveal critical mechanisms leading to enlargement.

Methods: The authors examined hemodynamic models of 67 longitudinally followed aneurysms, identifying 88 growth regions.

View Article and Find Full Text PDF

Background: Healthy individuals demonstrate considerable heterogeneity upon dynamic quantitative sensory testing assessment of endogenous pain modulatory mechanisms. For those who stratify into a 'pro-nociceptive profile' cohort, consisting of inefficient conditioned pain modulation (CPM) and elevated temporal summation of pain (TSP), the optimal approach for balancing the net output of pain modulatory processes towards anti-nociception remains unresolved. In this translational healthy human and rat study, we examined whether descending modulation countered spinal amplification during concurrent application of a CPM and TSP paradigm alongside pupillometry since pontine activity was previously linked to functionality of endogenous pain modulatory mechanisms and pupil dilation.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!