At present non-cardiac surgery is infrequent in patients survived after heart transplantations. The authors review specific features of general anesthesia in such a clinical situation on the basis of their own two clinical observations and literature data. The principles for the anesthesiological management are analysed. They are specific sterility rules, atypical mechanisms of cardio-vascular system adaptation to stress and peculiar reaction of a denervated heart to pharmacological agents.

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