Nonspecific and selected determinants of humoral immunity have been evaluated in 122 patients who clinically presented with "chronic salpingo-oophoritis". An objective confirmatory study is laparoscopy. The patients with clinical presentations of chronic salpingo-oophoritis displayed depressed phagocytic activity of neutrophils and function of complement in its both pathways. Alternatively, humoral immune parameters (serum levels of immunoglobulins A, M, G and circulating immune complexes) were normal. Functional evaluation of the classical and alternative complement activation pathways may provide a noninvasive objective test for differential diagnosis of chronic salpingo-oophoritis.

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