Carbon dioxide injection into deep saline formations may induce large-scale pressure increases and migration of native fluid. Local high-conductivity features, such as improperly abandoned wells or conductive faults, could act as conduits for focused leakage of brine into shallow groundwater resources. Pressurized brine can also be pushed into overlying/underlying formations because of diffuse leakage through low-permeability aquitards, which occur over large areas and may allow for effective pressure bleed-off in the storage reservoirs. This study presents the application of a recently developed analytical solution for pressure buildup and leakage rates in a multilayered aquifer-aquitard system with focused and diffuse brine leakage. The accuracy of this single-phase analytical solution for estimating far-field flow processes is verified by comparison with a numerical simulation study that considers the details of two-phase flow. We then present several example applications for a hypothetical CO2 injection scenario (without consideration of two-phase flow) to demonstrate that the new solution is an efficient tool for analyzing regional pressure buildup in a multilayered system, as well as for gaining insights into the leakage processes of flow through aquitards, leaky wells, and/or leaky faults. This solution may be particularly useful when a large number of calculations needs to be performed, that is, for uncertainty quantification, for parameter estimation, or for the optimization of pressure-management schemes.
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Clin Ther
January 2025
Department of Mechanical, Energy and Materials Engineering, School of Industrial Engineering, University of Extremadura, Badajoz, Spain.
Purpose: The aim of this study was to propose a lateral oscillating device for the prevention of pressure ulcers by understanding the mechanisms of tissue protection in healthy individuals during prolonged decubitus. We also sought to determine the optimal time interval for oscillation, considering peak pressure peaks and tolerable pressure limits as a function of individual characteristics such as age, weight, height, gender, and BMI.
Methods: A quasi-experimental, descriptive and analytical observational study was conducted between January 2022 and June 2023 with a sample of 25 healthy volunteers.
J Biomech Eng
January 2025
Department of Mechanical Engineering Marshall University, Huntington, WV 25755, USA; Department of Biomedical Engineering Marshall University, Huntington, WV 25755, USA.
Cell-laden, scaffold-based tissue engineering methods have been successfully utilized for the treatment of bone fractures. In such methods, the rate of scaffold biodegradation, transport of nutrients, and removal of cell metabolic wastes are critical fluid-dynamics factors, affecting tissue regeneration. Therefore, there is a critical need to identify the underlying material transport mechanisms associated with stem cell-driven, scaffold-based bone tissue regeneration.
View Article and Find Full Text PDFMaterials (Basel)
December 2024
Centre of Materials and Civil Engineering for Sustainability (C-MADE), University of Trás-os-Montes and Alto Douro (UTAD), 5000-801 Vila Real, Portugal.
Permeable asphalt pavement (PAP) is an efficient solution to stormwater management, allowing water to infiltrate through its layers. This reduces surface runoff and mitigates urban flooding risks. In addition to these hydrological benefits, PAP enhances water quality by filtering pollutants such as organic and inorganic materials and microplastics.
View Article and Find Full Text PDFNat Commun
January 2025
School of Petroleum Engineering, China University of Petroleum (East China), Qingdao, China.
Hydrogen is a promising clean energy source with geological reserves widely distributed globally, offering an annual flow exceeding 23 trillion grams. However, natural hydrogen extraction wells face unique safety challenges compared to conventional oil and gas wells. This paper reviews well safety concerns such as tubing/casing damage, cement/sealant failure, and excessive annular pressure buildup.
View Article and Find Full Text PDFSoc Sci Med
December 2024
ESHPM, Erasmus University Rotterdam, the Netherlands.
Capacity problems in healthcare lead organizations to seek new and fluid ways of organizing care to safeguard access to services. Task reallocation, triage and stepped care models are increasingly foregrounded as promising interventions that enhance the capacity, efficiency, and resilience of medical services and through which access can be maintained for a growing client base. In this paper, we argue that interventions meant to enhance capacity and increase efficiency have their limits in a system that is already under strain.
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